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SAPHO: Has the Time Come for Tailored Therapy?

Figueiredo, AS; Oliveira, AL; Caetano, A; Moraes-Fontes, MF

SAPHO (synovitis, acne, pustulosis, hyperostosis and osteitis) syndrome is a heterogeneous condition combining osteoarticular and cutaneous manifestations. Conventional treatments are mostly ineffective. We hereby report two patients, the first with an aggressive form of disease and the second with an incomplete response to two different anti-TNF-α agents. Both were successfully treated with tocilizumab and ust...

Date: 2020   |   Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
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