44 documents found, page 1 of 5

Circular economy in the restaurant sector: do practices go hand in hand?

The growing importance of sustainability has led the restaurant sector to explore circular economy practices to reduce waste and improve resource efficiency. This ongoing study examines the correlation between the adoption of one circular economy practice and the implementation of another within the restaurant sector. The study aims to identify specific practices that are related and assess the extent of these ...

LENT score in prognostic assessment of malignant pleural effusion – the impact ...

Introduction: Malignant pleural effusion (MPE) is a common manifestation in patients with advanced lung cancer. The LENT score was developed as a risk stratification system to predict the survival of these patients. However, following the discovery of molecular markers and a new era of personalized therapy, prognostic estimation became a challenging exercise. The aim of this study was to evaluate the performanc...

Comprehensive Evaluation of Peripheral Immunodynamics in Advanced Non-Small Cel...

Introduction: Immunotherapy, particularly immune checkpoint inhibitors (ICIs), has transformed the treatment landscape for advanced non-small cell lung cancer (NSCLC). Despite significant benefits for some patients, durable responses are limited to 20%–30% of cases, necessitating predictive biomarkers for better therapeutic guidance. While tumor-based markers such as PD-L1 expression and tumor mutational burden...

Competences developed in the internship context: perception of the graduates in...

This case study aims to understand the transversal and technical skills that graduates of the degree in Multimedia Communication from the Politécnico da Guarda developed during the internship period. In this sense, three objectives were defined: (1) to list the transversal skills developed by the students of the degree in Multimedia Communication during the internship in the academic years 2018/2019, 2019/2020 ...

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Salty Bronchorrhea: The Forgotten Semiology of Bronchioloalveolar Adenocarcinomas

Two-year treatment with Pembrolizumab monotherapy in advanced non-small cell lu...

Introduction and objectives: Immunotherapy has introduced advances in the treatment of non -small cell lung cancer. However, data from current clinical practice on potential responder groups, optimal duration of treatment and safety issues remain unclear. It is intended to produce a reflection on the population of patients with a favourable response to Pembrolizumab and how they have evolved clinically over tim...

Intervenção alimentar e nutricional na prevenção de deficiências intelectuais e...

<jats:p>A fenilcetonúria é uma doença que resulta de um erro congénito autossómico recessivo do metabolismo da fenilalanina. Este distúrbio provoca elevações nas concentrações plasmáticas deste aminoácido acarretando graves problemas ao nível do sistema nervoso. De acordo com a evidência encontrada, a introdução do recém-nascido em programas de rastreio neonatais específicos, parece melhorar e proporcionar nest...

Targeting circulating labile heme as a defense strategy against malaria

Severe presentations of malaria emerge as Plasmodium (P.) spp. parasites invade and lyse red blood cells (RBC), producing extracellular hemoglobin (HB), from which labile heme is released. Here, we tested whether scavenging of extracellular HB and/or labile heme, by haptoglobin (HP) and/or hemopexin (HPX), respectively, counter the pathogenesis of severe presentations of malaria. We found that circulating labil...

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