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Geriatric Assessment in Nephrology

Aging is one of the greatest challenges of the 21st century. "Chronic kidney disease (CKD) is highly prevalent in geriatric patients, but its management requires particular consideration due to the high heterogeneity of this population.". Comprehensive geriatric assessment (CGA), encompassing the identification of frailty and other geriatric syndromes, can modify prognostic outcomes, including quality of life, ...

Comparative Analysis of Caregivers’ Perspective from Patients under Hemodialysi...

Introduction: Elderly patients with advanced chronic kidney disease (CKD) experience a significant physical and emotional burden, regardless of treatment choice. However, little is known about the challenges faced by their families throughout the disease. This study aimed to evaluate how caregivers of patients over 75 years‑old with advanced CKD perceive and cope with the disease. Methods: A qualitative study w...

Chronic Kidney Disease: Supportive and Conservative Care in Portugal in 2023

Introduction: Elderly patients with chronic kidney disease (CKD) present a higher risk of becoming frail, a consequence of several comorbidities and worse functional status. This condition does not necessarily improve with the initiation of dialysis. Conservative care offers an option to treat elderly and/or frail patients with advanced CKD, which focuses on improving the patient’s quality of life, active sympt...

Effective Communication: A Foundation in Chronic Kidney Disease (CKD) Care

Chronic Kidney Disease: Supportive and Conservative Care in Portugal in 2023

Introduction: Elderly patients with chronic kidney disease (CKD) present a higher risk of becoming frail, a consequence of several comorbidities and worse functional status. This condition does not necessarily improve with the initiation of dialysis. Conservative care offers an option to treat elderly and/or frail patients with advanced CKD, which focuses on improving the patient’s quality of life, active sympt...

Population wide testing pooling strategy for SARS-CoV-2 detection using saliva

SARS-CoV-2 pandemic has forced frequent testing of populations. It is necessary to identify the most cost-effective strategies for the detection of COVID-19 outbreaks. Nasopharyngeal samples have been used for SARS-CoV-2 detection but require a healthcare professional to collect the sample and cause discomfort and pain to the individual. Saliva has been suggested as an appropriate fluid for the diagnosis of COV...

Effects of Rare Earth Elements on aquatic organisms under a changing environment

O aumento da disponibilidade de elementos terras raras (REE) e as alterações climáticas constituem um desafio ambiental com consequências pouco conhecidas; daí, o objetivo desta tese de doutoramento consistiu em investigar a sua bioacumulação, eliminação e interação através da avaliação de estratégias bioquímicas de diversos grupos taxonómicos (esponjas, peixes, bivalves e algas). Os resultados mostram que espé...

Impaired antioxidant defenses and DNA damage in the European glass eel (Anguill...

The European eel (Anguilla anguilla) has attracted scientific inquiry for centuries due to its singular biological traits. Within the European Union, glass eel fisheries have declined sharply since 1980, from up to 2000 t (t) to 62.2 t in 2018, placing wild populations under higher risk of extinction. Among the major causes of glass eels collapse, climate change has become a growing worldwide issue, specificall...

Differential tissue accumulation in the invasive Manila clam, Ruditapes philipp...

Among the environmental emerging concern rare earth elements, lanthanum (La) is one of the most common and reactive. Lanthanum is widely used in numerous modern technologies and applications, and its intense usage results in increasing discharges into the environment, with potentially deleterious consequences to earthlings. Therefore, we exposed the important food resource and powerful monitoring tool Manila cl...

Warming enhances lanthanum accumulation and toxicity promoting cellular damage ...

Cumulative and continuing human emissions of greenhouse gases to the atmosphere are causing ocean warming. Rising temperature is a major threat to aquatic organisms and may affect physiological responses, such as acid-base balance, often compromising species fitness and survival. It is also expected that warming may influence the availability and toxicological effects of pollutants, including Rare Earth Element...