31 documents found, page 1 of 4
IPATIMUP: Origins and Development of a Center of Scientific Excellence in Resea...
Filipe Costa, Lia; Ricon Ferraz, Amélia; Figueiredo, C.We examined the history and the impact of the Institute of Molecular Pathology and Immunology of the University of Oporto (IPATIMUP), one of Portugal’s most influential scientific institutions. Based on interviews with researchers and collaborators, as well as on an extensive review of bibliographic and institutional sources, this study explores the motivations behind its creation, the challenges faced, and the...
The impact of trait anxiety and autism traits on olfactory abilities of the gen...
Barros, F.; Figueiredo, C.; Costa, A.; Morais, S.; Madeira, N.; Soares, S.Introduction: Autism Spectrum Disorders (ASD) are characterized by atypical sensory processing, including in olfactory domain. However, since ASD is a complex condition characterized by marked heterogeneity in severity and symptoms, variables with significant manifestation in this condition, such as trait anxiety, may have been adding confounds to results. Importantly, perceptual abnormalities found in ASD seem...
Combining nucleic acid mimics and spectral imaging with fluorescence in situ hy...
Azevedo, Andreia S.; Teixeira, H.; Ferreira, R.; Figueiredo, C.; Wengel, J.; Almeida, Carina; Azevedo, N. F.[Excerpt] Nucleic acid mimics (NAMs)- based assays, such as locked nucleic acid/2′-O- methyl-RNA- fluorescence in vivo hybridization (LNA/2′OMe- FISH), have been developed for the identification and spatial location of Helicobacter pylori directly in the stomach. While H. pylori is considered the main gastric pathogen, there is a diverse range of stomach colonizers that may be associated with disease in the sto...
Prenatal Diagnosis and Management of a Fetal Goiter Hypothyroidism due to Dysho...
Figueiredo, C.; Falcão, I.; Vilaverde, J.; Freitas, J.; Oliveira, M.; Godinho, C.; Dores, J.; Rodrigues, M.; Carvalho, C.; Borges, T.Fetal goiter is a rare disorder not expected to be found during a healthy woman's pregnancy. It can be a prenatal manifestation of congenital hypothyroidism due to thyroid dyshormonogenesis and it can lead to serious perinatal complications. A vascularized fetal neck mass was detected at 29 weeks' gestation of a healthy primigravida. Magnetic resonance was suggestive of goiter causing airway deviation without p...
Intracellular delivery of oligonucleotides in Helicobacter pylori by fusogenic ...
Santos, R.S.; Dakwar, G.R.; Zagato, E.; Brans, T.; Figueiredo, C.; Raemdonck, K.; Azevedo, N.F.; De Smedt, S.C.; Braeckmans, K.
Evolução da Saúde Escolar em Portugal: Revisão Legislativa no Âmbito da Educação
Rocha, A.; Marques, A.; Figueiredo, C.; Almeida, C.; Batista, I.; Almeida, J.Este artigo tem como objetivo apresentar o percurso da Saúde Escolar em Portugal. Abarca a análise de diversa literatura no âmbito da Educação e a construção de um pensamento reflexivo acerca da sua história. A primeira referência à Saúde Escolar data de 1901, evoluiu até aos nossos dias e passou por etapas diversas. Ao longo deste percurso, salientam-se, como momentos relevantes, nalgumas escolas, a existência...
FISHji: new ImageJ macros for the quantification of fluorescence in epifluoresc...
Fontenete, S.; Carvalho, D.; Lourenço, Anália; Guimarães, N.; Madureira, P.; Figueiredo, C.; Azevedo, N. F.Fluorescence in situ hybridization (FISH) is based on the use of fluorescent staining dyes, however, the signal intensity of the images obtained by microscopy is seldom quantified with accuracy by the researcher. The development of innovative digital image processing programs and tools has been trying to overcome this problem, however, the determination of fluorescent intensity in microscopy images still has is...
Wage differentials in domestic work: The impact of contractual arrangements
Suleman, F.; Figueiredo, C.The regulation of employment relationships dates back to the process of industrialization where workers had dangerous and injurious working conditions. However, pervasive poor conditions, together with a wide range of contractual arrangements, demand additional efforts from national and international institutions. The Employment Relationship Recommendation (Recommendation 198) (ILO 2006) and the Decent Work Age...
Análise de vozes normais e patológicas por mulheres disfónicas
Quintal, A.; Correia, P.; Figueiredo, C.; Martins, P. A.
A case of Protracted Diarrhea in a Newborn: a Diagnostic Challenge
Mendes, C.; Figueiredo, C.; Mansilha, H.; Proença, E.; Oliveira, D.; Lima, R.; Carvalho, C.Congenital diarrhea comprises a broad range of pathologies and often requires a thorough workup and immediate treatment. Although rare, microvillous inclusion disease (MVID) should be included in differential diagnosis of this presentation in the neonate. We report the case of a 36-week newborn who developed signs of severe dehydration and lethargy, requiring fluid resuscitation and total parenteral nutrition. ...