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Distribution of community pharmacies and primary healthcare centers in Portugal...

Negrão, G; Moreira, R; Chaves Neves, I; Figueiredo, IV; Fernandez Llimos, F

Introduction: Poor access to community pharmacies has been associated with restricted accessibility to medicines. We aimed to compare the geographic distribution of community pharmacies and healthcare centers (HCCs) and identify sociodemographic variables associated with geographical discrepancies at the municipal level in Portugal. Methods: Data on HCC, physicians, pharmacies, and pharmacists were collected at...


Impact of the COVID-19 pandemic on antidepressant consumption in the Central re...

Negrao, LG; Coelho, C; Castel-Branco, MM; Figueiredo, IV; Fernandez-Llimos, F

PurposeTo evaluate the impact of the pandemic on the consumption of antidepressive agents in Central Portugal.MethodsTo estimate the causal effect of the pandemic an interrupted time series analysis was conducted. Data of antidepressant drugs monthly dispensed in community pharmacies between Jan-2010 and Dec-2021 were provided by the regional Health Administration. Anti-Parkinson dopaminergic agents and statins...


PERFORMANCE OF THE MEDICATION ADHERENCE UNIVERSAL QUESTIONNAIRE (MAUQ) IN PATIE...

Fortunato, AR; Araujo, A; Barbosa, C; Cunha, D; Costa, J; Silva, M; Ferreira, S; Cabral, AC; Branco, MC; Figueiredo, IV; Fernandez-Llimos, F


Performance of the Medication Adherence Universal Questionnaire (MAUQ) in patie...

Fortunato, AR; Araújo, A; Barbosa, C; Cunha, D; Costa, J; Silva, M; Ferreira, S; Cabral, AC; Castel Branco, M; Figueiredo, IV; Fernandez Llimos, F


Development and validation of a Medication Adherence Universal Questionnaire: t...

Cabral, AC; Lavrador, M; Castel Branco, M; Figueiredo, IV; Fernandez Llimos, F

BackgroundDifferent questionnaires assess self-reported medication adherence and others quantify aspects of patients attitudes towards medication, but not together in a single instrument. Gathering these two aspects in a single instrument could reduce patients survey burden.AimThe aim of this study was to develop the Medication Adherence Universal Questionnaire (MAUQ) using the Maastricht Utrecht Adherence in H...


A Universal Pharmacological-Based List of Drugs with Anticholinergic Activity

Lavrador, M; Cabral, AC; Verissimo, MT; Fernandez-Llimos, F; Figueiredo, IV; Castel-Branco, MM

Anticholinergic burden tools have relevant pharmacological gaps that may explain their limited predictive ability for clinical outcomes. The aim of this study was to provide a universal pharmacological-based list of drugs with their documented affinity for muscarinic receptors. A comprehensive literature review was performed to identify the anticholinergic burden tools. Drugs included in these instruments were ...


Discrepancies among equations to estimate the glomerular filtration rate for dr...

Castel Branco, MM; Lavrador, M; Cabral, AC; Pinheiro, A; Fernandes, J; Figueiredo, IV; Fernandez Llimos, F

BackgroundPatients often require adjustments to drug doses due to impaired renal function. Glomerular filtration rate (GFR) estimation using various equations can result in discrepancies, potentially leading to different dose adjustment recommendations.AimTo determine the clinical significance of discrepancies observed between different equations used to estimate GFR for drug dose adjustments in a real-world gr...


Evaluation of a sample of Portuguese hypertensive patients' knowledge about hyp...

Cabral, AC; Lavrador, M; Fernandez-Llimos, F; Castel-Branco, M; Figueiredo, IV

Introduction and objectives: Patient knowledge about hypertension is an important patient-related determinant for poor blood pressure control and is a target for more effective interventions. We aimed to evaluate hypertensive patients' knowledge and awareness about hypertension and its influence on their beliefs about their medication and their adherence to antihypertensive therapy. Methods: A cross-sectional s...


Evaluation of Cardiovascular Pharmacotherapy Guideline Adherence and Risk Facto...

Fonseca, A; Lima, TD; Fernandez-Llimos, F; Castel-Branco, MM; Figueiredo, IV

Background: Cardiovascular disease (CVD) remains the leading cause of death worldwide. Assessing the patients' CVD risk, controlling the risk factors, and ensuring the guideline-adherent cardiovascular pharmacotherapy are crucial interventions to improve health outcomes. This study aimed to evaluate the potential of pharmacists to improve the adherence to pharmacotherapy guidelines and the achievement of risk f...


Pharmacist-led medication reconciliation on admission to an acute psychiatric h...

Oliveira, J; Silva, TCE; Cabral, AC; Lavrador, M; Almeida, FF; Macedo, A; Saraiva, C; Fernandez Llimos, F; Caramona, MM; Figueiredo, IV

Background: Therapy management in patients suffering from mental health disorders is complex and the risks derived from changes or interruptions of treatment should not be ignored. Medication reconciliation in psychiatry may reduce medication errors and promote patient safety during transitions of care. Objective: To identify the influence of complementary information sources in the construction of the best pos...


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