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Evaluation of hemodynamic effects of xenon in dogs undergoing hemorrhagic shock

Franceschi, Ruben C.; Malbouisson, Luiz; Yoshinaga, Eduardo; Auler Jr., Jose Otavio Costa; Figueiredo, Luiz Francisco Poli de; Carmona, Maria Jose C.

OBJECTIVES: The anesthetic gas xenon is reported to preserve hemodynamic stability during general anesthesia. However, the effects of the gas during shock are unclear. The objective of this study was to evaluate the effect of Xe on hemodynamic stability and tissue perfusion in a canine model of hemorrhagic shock. METHOD: Twenty-six dogs, mechanically ventilated with a fraction of inspired oxygen of 21% and anes...

Data: 2013   |   Origem: Oasisbr





Mesenteric microcirculatory dysfunctions and translocation of indigenous bacter...

Zanoni, Fernando Luiz; Benabou, Simon; Greco, Karin Vicente; Moreno, Ana Carolina Ramos; Cruz, José Walber Miranda Costa; Filgueira, Fernando Paranaiba

PRUPOSE: Bacterial translocation has been shown to occur in critically ill patients after extensive trauma, shock, sepsis, or thermal injury. The present study investigates mesenteric microcirculatory dysfunctions, the bacterial translocation phenomenon, and hemodynamic/metabolic disturbances in a rat model of intestinal obstruction and ischemia. METHODS: Anesthetized (pentobarbital 50 mg/kg, i.p.) male Wistar ...

Data: 2009   |   Origem: Oasisbr


Sepsis: from bench to bedside

Silva, Eliézer; Passos, Rogério Da Hora; Ferri, Maurício Beller; Figueiredo, Luiz Francisco Poli de

Sepsis is a syndrome related to severe infections. It is defined as the systemic host response to microorganisms in previously sterile tissues and is characterized by end-organ dysfunction away from the primary site of infection. The normal host response to infection is complex and aims to identify and control pathogen invasion, as well as to start immediate tissue repair. Both the cellular and humoral immune s...

Data: 2008   |   Origem: Oasisbr



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