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Evaluation of three recombinant proteins for the development of ELISA and immun...

Santos, Anna Raquel Ribeiro dos; Serufo, Ângela Vieira; Figueiredo, Maria Marta; Godoi, Lara Carvalho; Vitório, Jéssica Gardone; Marcelino, Andreza Pain

BACKGROUND Visceral Leishmaniasis (VL) is an infectious disease that is a significant cause of death among infants aged under 1 year and the elderly in Brazil. Serodiagnosis is a mainstay of VL elimination programs; however, it has significant limitations due to low accuracy. OBJECTIVE This study aimed to evaluate three recombinant Leishmania infantum proteins (rFc, rC9, and rA2) selected from previous proteomi...

Date: 2019   |   Origin: Oasisbr

A potential link among antioxidant enzymes, histopathology, and trace elements ...

Souza, Carolina Carvalho de; Barreto, Tatiane Oliveira; Silva, Sydnei Magno da; Pinto, Aldair Junio Woyames; Figueiredo, Maria Marta

Canine visceral leishmaniasis (CVL) is a severe and fatal systemic chronic inflammatory disease. We investigated the alterations in, and potential associations among, antioxidant enzymes, trace elements and histopathology in CVL. Blood and tissue levels of Cu-Zn superoxide dismutase, catalase and glutathione peroxidase were measured in mixed-breed dogs naturally infected with Leishmania infantum chagasi, sympto...

Date: 2017   |   Origin: Oasisbr

Histopathological findings and detection of parasites in the eyes of dogs infec...

Brito, Fábio Luiz da Cunha; Laus, José Luiz [UNESP]; Tafuri, Wagner Luiz; Figueiredo, Maria Marta; Silva Júnior, Valdemiro Amaro

Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T19:00:12Z No. of bitstreams: 1 S0103-84782010000500022.pdf: 196691 bytes, checksum: 4a2839f9a86844112337d299323b3d30 (MD5); Made available in DSpace on 2013-08-22T19:00:12Z (GMT). No. of bitstreams: 1 S0103-84782010000500022.pdf: 196691 bytes, checksum: 4a2839f9a86844112337d299323b3d30 (MD5) Previous issue date: 2010-05-01; Made availabl...

Date: 2014   |   Origin: Oasisbr

American tegumentary leishmaniasis : effectiveness of an immunohistochemical pr...

Alves, Cibele Fontes; Alves, Cíntia Fontes; Figueiredo, Maria Marta; Souza, Carolina Carvalho de; Coelho, George Luiz Lins Machado; Melo, Maria Norma

Background: American tegumentary leishmaniasis (ATL) is endemic in Latin America, where Brazil has over 27 thousand cases per year. The aim of the present study was to develop an immunohistochemical method (IHC) for ATL diagnosis. For this purpose, we used serum from a dog naturally infected with Leishmania (L) infantum (canine hyperimmune serum) as the primary antibody, followed by a detection system with a se...

Date: 2014   |   Origin: Oasisbr

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