119 documents found, page 1 of 12
Tripeptides featuring dehydrophenylalanine and homophenylalanine: homo- versus ...
Carvalho, André F.; Pereira, Teresa; Oliveira, Carlos; Figueiredo, Pedro; Carvalho, Alexandra; Pereira, David M.; Hilliou, L.; Bañobre-López, ManuelOver the years, our research group developed dehydrodipeptides N-capped with aromatic moieties as protease-resistant efficacious hydrogelators, affording self-assembled hydrogels at low (critical) concentrations. Dehydrotripeptides, with different dipeptide sequences and (D,L) stereochemistry, open a wider chemical space for the development of self-assembled soft nanomaterials. In this work, a small library of ...
The role of Physical and Rehabilitation Medicine in Achondroplasia
Hovenkamp, Carla; Coelho, Alexandra P.; Figueiredo, Pedro; Veiros, Iolanda; Branco, João PauloAchondroplasia is the most common and most researched skeletal dysplasia. It is caused by a mutation in the fibroblast growth factor receptor 3 (FGFR3) gene, leading to abnormal endochondral ossification which causes multiple anatomical anomalies, the most characteristic being macrocephaly and asymmetrical short stature with proximal shortening of the limbs. The anatomical changes will result in organic and fun...
Prediction of Hepatocellular Carcinoma in a Portuguese Population after Hepatit...
Mascarenhas, André; Serrazina, Juliana; Bronze, Sérgio; Cortez-Pinto, Helena; Presa, José; Barreira, Ana; Carrola, Paulo; Vara-Luiz, FranciscoIntroduction: Chronic infection with hepatitis C virus (HCV) causes 25% of hepatocellular carcinoma (HCC) cases worldwide, a major cause of morbimortality even after sustained virologic response (SVR). Universal screening to all patients with advanced liver fibrosis is currently recommended. A risk-based strategy could improve the detection rate of early HCC and diminish the surveillance burden. Although severa...
Exploring the impact of ball possession directionality on youth footballers’ po...
Coutinho, Diogo; Gonçalves, Bruno; Kelly, Adam; Santos, Sara; Figueiredo, Pedro; Soares, Carlos; Travassos, BrunoThis study aimed to investigate the effects of manipulating ball possession directionality (i.e., NO direction, MULTI direction or ONE direction) on the physical, tactical and technical performance of youth football players during small-sided games (SSGs). A total of 18 male youth football players (age: 13.6 ± 0.4 years) participated in four testing days, where they completed three random order experimental tas...
Transvenous Obliteration Procedure in the Management of Parastomal Variceal Ble...
Estorninho, João; Patrão, Pedro; Temido, Maria José; Perdigoto, David N.; Figueiredo, Pedro; Donato, PauloIntroduction: Parastomal variceal bleeding (PVB) is a recognized complication of ostomized patients in the presence of portal hypertension. However, since there are few reported cases, a therapeutic algorithm has not yet been established. Case Presentation: A 63-year-old man, who had undergone a definitive colostomy, recurrently presented to the emergency department hemorrhage of bright red blood from his colos...
IgG4-Related Esophageal Disease Presenting as Esophagitis with Chronic Strictures
Correia, Catarina; Moreira, Hélder; Almeida, Nuno; Soares, Marta; Cipriano, Maria Augusta; Figueiredo, PedroIgG4-related disease is a recently recognized autoimmune systemic disorder that has been described in various organs. The disease is characterized histologically by a dense lymphoplasmacytic infiltrate with IgG4-positive cells, storiform fibrosis, obliterative phlebitis, and can be associated with space-occupying lesions. IgG4-related disease involving the upper gastrointestinal tract is rare. We report the cas...
Editorial: physiological and biomechanical determinants of swimming performance...
Castro, Flávio A. de Souza; Figueiredo, Pedro; Toubekis, Argyris G.; Barbosa, Tiago M.; McCabe, CarlaThe objective of this Research Topic was to develop and strengthen evidence of training and swimming performance to increase scientific knowledge in the area, considering that understanding the biomechanical, physiological, and neuromuscular determinants of swimming performance is still challenging. This way, 13 manuscripts have been reviewed and approved for this research topic (volume II). We can categorize t...
Is hybrid therapy more efficient in the eradication of Helicobacter pylori infe...
Temido, Maria José; Mbanze, Dara; Almeida, Nuno; Oliveiros, Bárbara; Gravito-Soares, Elisa; Figueiredo, PedroIntroduction Hybrid therapy (HT) is a non-bismuth quadruple therapy created to surpass Helicobacter pylori’s (H. pylori) resistance rates to antibiotics. HT has excellent eradication rates, as well as a very good compliance and safety profile. We aim to compare HT with sequential therapy (ST) and concomitant therapy (CT) for the eradication of H. pylori. Methods This systematic review was conducted following th...
Urban rehabilitation and tourism: lessons from Porto (2010–2020)
Fernandes, José; Chamusca, Pedro; Pinto, Jorge; Tenreiro, José; Figueiredo, PedroCities experience rapid growth and transformation. Over the past decades, change has been particularly intense and complex, associated to globalization, spatial compression and temporal acceleration. Within this context, the EU funds introduced new urban rehabilitation dynamics that made a city center more and more attractive. This, alongside the growth of international tourism, has increased the number of city...
Urban rehabilitation and tourism: lessons from Porto (2010-2020)
Fernandes, José Alberto Rio; Chamusca, Pedro; Pinto, Jorge; Tenreiro, José; Figueiredo, PedroCities experience rapid growth and transformation. Over the past decades, change has been particularly intense and complex, associated to globalization, spatial compression and temporal acceleration. Within this context, the EU funds introduced new urban rehabilitation dynamics that made a city center more and more attractive. This, alongside the growth of international tourism, has increased the number of city...