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Effect of blueberry supplementation on a diet-induced rat model of prediabetes—...

Ferreira, Gonçalo; Vieira, Pedro; Alves, André; Nunes, Sara; Preguiça, Inês; Martins-Marques, Tânia; Ribeiro, Tânia; Girão, Henrique; Figueirinha, Artur

Blueberries, red fruits enriched in polyphenols and fibers, are envisaged as a promising nutraceutical intervention in a plethora of metabolic diseases. Prediabetes, an intermediate state between normal glucose tolerance and type 2 diabetes, fuels the development of complications, including hepatic steatosis. In previous work, we have demonstrated that blueberry juice (BJ) supplementation benefits glycemic cont...


Effect of Thymbra capitata (L.) Cav. on Inflammation, Senescence and Cell Migra...

Silva, Jorge M. Alves; Pedreiro, Sónia; Cavaleiro, Carlos; Cruz, M. Teresa; Figueirinha, Artur; Salgueiro, Lígia

Aromatic plants are reported to display pharmacological properties, including anti-aging. This work aims to disclose the anti-aging effect of the essential oil (EO) of Thymbra capitata (L.) Cav., an aromatic and medicinal plant widely used as a spice, as well as of the hydrodistillation residual water (HRW), a discarded by-product of EO hydrodistillation. The phytochemical characterization of EO and HRW was ass...


Exploiting the Crithmum maritimum L. Aqueous Extracts and Essential Oil as Pote...

Pedreiro, Sónia; Figueirinha, Artur; Cavaleiro, Carlos; Cardoso, Olga; Donato, Maria Manuel; Salgueiro, Lígia; Ramos, Fernando

Chritmum maritimum, sea fennel, is a facultative halophyte used in salads, soups, and sauces, as well as used to prepare medicinal juices and aqueous extracts (AE) to treat several ailments. Its essential oil (EO) is used as a spice and aromatizing. In this work, the nutritional (crude protein, fiber, lipids, and ashes content) and HPLC-PDA phenolic profiles were determined. Furthermore, the antioxidant potenti...


Vascular effects of Fragaria vesca L. in human arteries

Malheiros, Jéssica; Simões, Daniela M.; Antunes, Pedro E.; Figueirinha, Artur; Cotrim, Maria Dulce; Fonseca, Diogo A.

Fragaria vesca L. (wild strawberry) is traditionally used for its anti-inflammatory activity and for gastrointestinal, cardiovascular and urinary disorders. A previous study with the rat aorta showed that its leaves extract elicits endothelium-dependent vasorelaxation. Our aim was to investigate the clinical application of Fragaria vesca in vascular disease, by assessing the vascular effects of an infusion and ...


The Chemical Profile, and Antidermatophytic, Anti-Inflammatory, Antioxidant and...

Correia, Edmilson Emanuel Monteiro; Figueirinha, Artur; Rodrigues, Lisa; Pinela, José; Calhelha, Ricardo C.; Barros, Lillian; Fernandes, Chantal

Withania chevalieri, endogenous from Cape Verde, is a medicinal plant used in ethnomedicine with a large spectrum of applications, such as treating skin fungal infections caused by dermatophytes. The aim of this work was to chemically characterize the W. chevalieri crude ethanolic extract (WcCEE), and evaluate its bioactivities as antidermatophytic, antioxidant, anti-inflammatory and anticancer, as well as its ...


The chemical profile, and antidermatophytic, anti-inflammatory, antioxidant and...

Correia, Edmilson Emanuel Monteiro; Figueirinha, Artur; Rodrigues, Lisa; Pinela, José; Calhelha, Ricardo C.; Barros, Lillian; Fernandes, Chantal

Withania chevalieri, endogenous from Cape Verde, is a medicinal plant used in ethnomedicine with a large spectrum of applications, such as treating skin fungal infections caused by dermatophytes. The aim of this work was to chemically characterize the W. chevalieri crude ethanolic extract (WcCEE), and evaluate its bioactivities as antidermatophytic, antioxidant, anti-inflammatory and anticancer, as well as its ...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Chemical Composition and Effect against Skin Alterations of Bioactive Extracts ...

Moreira, Patrícia; Sousa, Fábio Jesus; Matos, Patrícia; Brites, Gonçalo Sousa; Gonçalves, Maria José; Cavaleiro, Carlos; Figueirinha, Artur

Eucalyptus globulus is planted extensively for pulp, paper and wood production. Although bioactive compounds obtained from its biomass are used as cosmetics ingredients, the skin effects were not yet fully explored. In order to fill this gap, this work aimed to study the protective effect against skin damage provided by the essential oil (EO) obtained from the hydrodistillation of Eucalyptus globulus leaves, an...


Luteolin Improves Perivascular Adipose Tissue Profile and Vascular Dysfunction ...

Queiroz, Marcelo; Leandro, Adriana; Azul, Lara; Figueirinha, Artur; Seiça, Raquel; Sena, Cristina M.

We investigated the effects of luteolin on metabolism, vascular reactivity, and perivascular adipose tissue (PVAT) in nonobese type 2 diabetes mellitus animal model, Goto-Kakizaki (GK) rats. Methods: Wistar and GK rats were divided in two groups: (1) control groups treated with vehicle; (2) groups treated with luteolin (10 mg/kg/day, for 2 months). Several metabolic parameters such as adiposity index, lipid pro...


Seaweeds’ carbohydrate polymers as plant growth promoters

Pacheco, Diana; Cotas, João; Rocha, Carolina P.; Araújo, Glacio S.; Figueirinha, Artur; Gonçalves, Ana M. M.; Bahcevandziev, Kiril; Pereira, Leonel

Currently, the high food demand led to a mass agriculture practices, whereas crop productivity is one of the major concerns for the producers. However, the intensification of the use of synthetic fertilizers has led to serious harmful impacts for human health and for the environment. The quest for novel and natural agricultural products is a current trend, hence seaweed polysaccharide bioactivity can contribute...


Formulation Effects in the Antioxidant Activity of Extract from the Leaves of C...

Sousa, Raquel; Figueirinha, Artur; Batista, Maria Teresa; Pina, Maria Eugénia

Cymbopogon citratus DC (Stapf.) is a perennial grass and it is distributed around the world. It is used as a condiment for food and beverage flavouring in the form of infusions and decoctions of its dried leaves. Our previous studies have shown antioxidant, anti-inflammatory and gastroprotective activities for the infusion and its phenolic fractions. The aim of the present work was to develop oral dosage forms ...


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