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Genotype®MTBDRplus and Xpert®MTB/RIF in the diagnosis of tuberculosis and resis...

Soares,Valéria Martins; Almeida,Isabela Neves de; Vater,Maria Cláudia; Alves,Suely; Figueredo,Lida Jouca de Assis; Scherer,Luciene

Abstract INTRODUCTION: The present study sought to assess the mean and activity based cost (ABC) of the laboratory diagnosis for tuberculosis through the application of conventional and molecular techniques-Xpert®MTB/RIF and Genotype®MTBDRplus-in a tertiary referral hospital in Brazil. METHODS: The mean cost and ABC formed the basis for the cost analysis of the TB laboratory diagnosis. RESULTS: The mean cost an...

Date: 2020   |   Origin: Oasisbr

Cost analysis of smear microscopy and the Xpert assay for tuberculosis diagnosi...

Figueredo,Lida Jouca de Assis; Miranda,Silvana Spíndola de; Santos,Lucas Benício dos; Manso,Caroline Gontijo Gonçalves; Soares,Valéria Martins

Abstract INTRODUCTION: Rapid and accurate tuberculosis detection is critical for improving patient diagnosis and decreasing tuberculosis transmission. Molecular assays can significantly increase laboratory costs; therefore, the average time and economic impact should be evaluated before implementing a new technology. The aim of this study was to evaluate the cost and average turnaround time of smear microscopy ...

Date: 2020   |   Origin: Oasisbr

Detection of Drug Resistant Mycobacterium Tuberculosis Strains Using Kit SIRE N...

Miranda,Silvana Spindola de; Almeida,Isabela Neves de; Mansur,Maria de Fátima Filardi Oliveira; Figueredo,Lida Jouca de Assis; Carvalho,Wânia da Silva

Abstract (1) Background: The Commercial Kit SIRE Nitratase® PlastLabor, is a drug susceptibility test kit used to detect Mycobacterium tuberculosis resistance to first-line TB treatment drugs. The present study aimed at evaluating its performance in a multicenter study. (2) Methods: To determine its accuracy, the proportion methods in Lowenstein Jensen medium or the BACTECTMMGITTM960 system was used as a gold s...

Date: 2020   |   Origin: Oasisbr

Factors associated with tuberculosis and multidrug-resistant tuberculosis in pa...

Soares,Valéria Martins; Almeida,Isabela Neves de; Figueredo,Lida Jouca de Assis; Haddad,João Paulo Amaral; Oliveira,Camila Stefanie Fonseca de

ABSTRACT Objective: To evaluate the risk factors for the development of tuberculosis and multidrug-resistant tuberculosis (MDR-TB) in patients treated at a tertiary referral hospital. Methods: This was a cross-sectional study based on data obtained from patients treated at the Júlia Kubitschek Hospital, located in the city of Belo Horizonte, Brazil, between October of 2012 and October of 2014. We evaluated soci...

Date: 2020   |   Origin: Oasisbr

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