8 documents found, page 1 of 1
Tumor-Infiltrating T Cells in Skin Basal Cell Carcinomas and Squamous Cell Carc...
Cunha, D; Neves, M; Silva, D; Silvestre, AR; Nunes, PB; Arrobas, F; Ribot, JC; Ferreira, F; Moita, LF; Soares-de-Almeida, L; Silva, JM; Filipe, PBasal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) are high-incidence, non-melanoma skin cancers (NMSCs). The success of immune-targeted therapies in advanced NMSCs led us to anticipate that NMSCs harbored significant populations of tumor-infiltrating lymphocytes with potential anti-tumor activity. The main aim of this study was to characterize T cells infiltrating NMSCs. Flow cytometry and immuno...
Epidemiology of Psoriasis in Portugal: A Population-Based Study
Torres, T; Filipe, P; Menezes Brandão, F; Figueiredo, A; Pinto Soares, A; Sousa Basto, A; Rebelo, C; Correia, O; Ferreira, P; Brasileiro, AIntroduction: Psoriasis is a common, chronic, and inflammatory skin disorder with a high personal, social and economic burden and important implica-tions for healthcare systems. The aim of this study was to provide an epidemiological characterization of individuals with psoriasis in Portugal.Material and Methods: A large observational, cross-sectional, nationwide, population-based survey study developed by the ...
Portuguese Position Paper on the Use of Biosimilars in Psoriasis
Torres, T; Ferreira, A; Ferreira, P; Henriques, M; Leite, L; Magina, S; Marques Pinto, G; Oliveira, H; Sousa Basto, A; Tavares Bello, R; Varela, P
Portuguese Position Paper on the Use of Biosimilars in Psoriasis
Torres, T; Ferreira, A; Ferreira, P; Henriques, M; Leite, L; Magina, S; Marques Pinto, G; Oliveira, H; Sousa Basto, A; Tavares Bello, R; Varela, P
Churg-Strauss syndrome: a disabling disease.
André, M C; Fraga, A; Reis, M Duarte; Filipe, P; Soares de Almeida, L M; Marques Gomes, M AChurg-Strauss syndrome (CSS) is an infrequent vasculitis that affects small to medium-sized vessels. We describe a 51 year-old-female admitted to our inpatient unit with bullae on her right foot and forearm with pain, paresthesias and impotence of the foot. There was rapid clinical deterioration with lost of gait and peripheral eosinophilia. Histopathology showed many extravascular eosinophils. Bone marrow had ...
Normas de Boa Prática para o Tratamento da Psoríase em Placas em Idade Não Pedi...
Marques Pinto, G; Filipe, PA psoríase é uma dermatose inflamatória, que afecta cerca de 2% da população mundial, com envolvimento preferencial cutâneo e articular, mas frequentemente associada a co-morbilidades importantes. Cerca de 20-30% dos doentes têm formas moderadas a graves, não controláveis por tratamentos tópicos. As terapêuticas sistémicas clássicas – PUVAterapia oral, retinóides, ciclosporina e metotrexato – podem induzir toxi...
Apoptosis is a prominent feature of human alcoholic and non-alcoholic steatohep...
Rodrigues, CM; Cortez-Pinto, H; Sola, S; Filipe, P; Baptista, A; Camilo, ME; De Moura, MC
Fluorescent products in the crystalline lens of type ii diabetic patients.
Silva, J; Freitas, J P; Filipe, P; Vendrell, E; Rodrigo, F GA body of evidence suggests that glycation of proteins and the resulting fluorescent products take part in the late complications of diabetes. The purpose of this study was to analyse the fluorescence of lens soluble proteins from diabetic patients. Soluble proteins were obtained from lens with cataract from 20 type II diabetic patients and from 21 non diabetic controls with similar age. The fluorescence of the...