8 documents found, page 1 of 1
Weighted maximum likelihood estimation for individual growth models
Jacinto, Gonçalo; Filipe, Patrícia; Braumann, CarlosWe apply a class of stochastic differential equations to model individual growth in a randomly fluctuating environment using cattle weight data. We have used maximum likelihood theory to estimate the parameters. However, for cattle data, it is often not feasible to obtain animal's observations at equally spaced ages nor even at the same ages for different animals and there is typically a small number of observa...
Roots and rhizomes of wild Asparagus: nutritional composition, bioactivity and ...
Adouni, Khaoula; Júlio, Ana; Santos-Buelga, Celestino; González-Paramás, Ana M.; Filipe, Patrícia; Rijo, Patricia; Costa Lima, Sofia A.; Reis, SaletteThe nutritional composition and bioactive properties of roots and rhizomes of Asparagus stipularis were evalu- ated. Antioxidant activity of extracts obtained by infusion was evaluated using free radicals scavenging and reducing power methods. Porcine liver primary cell was used to check the hepatotoxicity of infusions. Results revealed that Asparagus samples are likely a source of nutrients, such as dietary fi...
Roots and rhizomes of wild Asparagus: Nutritional composition, bioactivity and ...
Adouni, Khawla; Júlio, Ana Carolina; Santos-Buelga, Celestino; González-Paramás, Ana María; Filipe, Patrícia; Rijo, Patrícia; Lima, Sofia A. CostaThe nutritional composition and bioactive properties of roots and rhizomes of Asparagus stipularis were evaluated. Antioxidant activity of extracts obtained by infusion was evaluated using free radicals scavenging and reducing power methods. Porcine liver primary cell was used to check the hepatotoxicity of infusions. Results revealed that Asparagus samples are likely a source of nutrients, such as dietary fibr...
Nanocarrier-mediated topical insulin delivery for wound healing
Macedo, Ana S.; Mendes, Francisca; Filipe, Patrícia; Reis, Salette; Fonte, PedroWound care has been clinically demanding due to inefficacious treatment that represents an economic burden for healthcare systems. In Europe, approximately 7 million people are diagnosed with untreated wounds, leading to a cost between 6.000€ and 10.000€ per patient/year. In the United States of America, 1.5 million people over 65 years old suffer from chronic wounds. A promising therapeutic strategy is the use...
Structured additive regression modeling of pulmonary tuberculosis infection
Sousa, Bruno de; Pires, Carlos; Gomes, Dulce; Filipe, Patrícia; Costa-Veiga, Ana; Nunes, CarlaTuberculosis (TB) is one of the top 10 causes of death and the leading cause of a single infectious agent (above HIV/AIDS). In 2017, the World Health Organization (WHO) estimated 10.0 million people developed TB and 1.3 million deaths (range, 1.2–1.4 million) among HIV-negative people with an additional 300 000 deaths from TB (range, 266 000–335 000) among HIVpositive people. Studies that understand the socio-d...
Spatiotemporal epidemiology in the identification of critical areas: an applica...
Nunes, Carla; Gomes, Dulce; Filipe, Patrícia; Areias, Cristiana; Sousa, Bruno; Briz, TeodoroThe increasing relevance of spatiotemporal epidemiology, enhanced by a greater availability of geographical information and the growing importance of knowing where, when and how the health phenomena occurred in a spatiotemporal context, promotes more scientifically robust and effective early intervention. The identification of critical areas, either in terms of their higher incidence of a disease, or their inte...
Pulmonary Tuberculosis and HIV/AIDS: joint space-time clustering under an epide...
Nunes, Carla; Briz, Teodoro; Gomes, Dulce; Filipe, PatríciaSince the mid-80s Tuberculosis declining trend became softer and even reversed in some countries. HIV/AIDS frequently appears as the main cause for the resurgence of Tuberculosis. This work aims at identifying critical areas for the joint occurrence of these conditions in Portugal, and at confirming the belief that HIV is not a major explanation for the slow Tuberculosis incidence decline. Based on correlation ...
Modelos de evolução do peso de animais em ambiente aleatório
Filipe, Patrícia; Braumann, CarlosApós uma breve revisão dos métodos usualmente utilizados para modelar o crescimento de animais, propõe-se como modelos descritivos gerais para a evolução do peso de animais em ambiente aleatório equações diferenciais estocásticas da forma: dX(t)=f(X(t))dt+sdW(t) (1) onde X(t) representa o peso (ou uma potência do peso) do animal na idade t, s mede a intensidade dos efeitos das perturbações aleatórias do ambient...