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UTILIZAÇÃO DE AZAMACROCICLOS E SUAS COMPOSIÇÕES COM ATIVIDADE ANTI-INCRUSTANTE

Filipe Mergulhão; L. G. Alves; E. R. Silva; J. H. Leitão; A. M. Martins; S. Almada; O. Ferreira; Sara Faria


Biomimetic Surfaces as a Potential Strategy to Mitigate Biofouling in the Food ...

Rita Santos; Fábio Carvalho; Luciana Gomes; Marta Lima; Ana Azevedo; Mohsin Amin; Mette Burmølle; Jelmer Sjollema; Filipe Mergulhão


Production and Characterization of Graphene Oxide Surfaces against Uropathogens

Belo, S; Sousa-Cardoso, F; Rita Teixeira dos Santos; Luciana Gomes; Vieira, R; Sjollema, J; Soares, OSGP; Filipe Mergulhão

Graphene and its functionalized derivatives have been increasingly applied in the biomedi-cal field, particularly in the production of antimicrobial and anti-adhesive surfaces. This study aimed to evaluate the performance of graphene oxide (GO)/polydimethylsiloxane (PDMS) composites against Staphylococcus aureus and Pseudomonas aeruginosa biofilms. GO/PDMS composites containing different GO loadings (1, 3, and ...


Exploring Nitrogen-Functionalized Graphene Composites for Urinary Catheter Appl...

Rita Teixeira dos Santos; Luciana Gomes; Vieira, R; Sousa Cardoso, F; Soares, SGP; Filipe Mergulhão

Graphene has been broadly studied, particularly for the fabrication of biomedical devices, owing to its physicochemical and antimicrobial properties. In this study, the antibiofilm efficacy of graphene nanoplatelet (GNP)-based composites as coatings for urinary catheters (UCs) was investigated. GNPs were functionalized with nitrogen (N-GNP) and incorporated into a polydimethylsiloxane (PDMS) matrix. The resulti...


Role of lactic acid bacteria (LAB) in displacing biofilms in the food industry

Rita Santos; Fábio Carvalho; Filipe Mergulhão; Luciana Gomes; Andreia Tomé


Development of Cork Biocomposites Enriched with Chitosan Targeting Antibacteria...

Fernandes, EM; Lobo, FCM; Faria, SI; Luciana Gomes; Silva, TH; Filipe Mergulhão; Rui Reis

The demand for bio-based and safer composite materials is increasing due to the growth of the industry, human population, and environmental concerns. In this framework, sustainable and safer cork-polymer composites (CPC), based on green low-density polyethylene (LDPE) were developed using melt-based technologies. Chitosan and polyethylene-graft-maleic anhydride (PE-g-MA) were employed to enhance the CPC's prope...


Biomimetic Surfaces from Cabbage Leaves: A Novel Approach to Prevent Biofilm Fo...

Rita Santos; Fábio Carvalho; Luciana Gomes; Marta Lima; Ana Azevedo; Mohsin Amin; Mette Burmølle; Jelmer Sjollema; Filipe Mergulhão


Antimicrobial properties of cationic steroids, method and uses thereof

Filipe Mergulhão; Ana Rita Neves; E. Sousa; E. Pinto; E. R. Silva; F. Durães; Marisa Gomes; M. Correia da Silva; P. Costa; Rita Santos; Joana Silva


Curcumin production by engineered Escherichia coli biofilms

Luciana Gomes; Ana Azevedo; Marta Ferreira; Gabriel Monteiro; Filipe Mergulhão


Use of bacterial biofilms to produce high added-value compounds

Ana Azevedo; Fábio M. Carvalho; Luciana Gomes; Filipe Mergulhão

In the past decades, progress has been made on the beneficial features of microbial biofilms for the production of biotechnological and industrial relevant substances. The use of biofilm reactors as biocatalysts has been established as an interesting approach in the production of valuable compounds, including antibiotics, enzymes, bioethanol, organic acids, and biohydrogen. Despite the potential of biofilm syst...


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