4 documents found, page 1 of 1
Long term in vivo performance of starch-based scaffolds
Santos, T. C.; Marques, A. P.; Castro, António G.; van Griensven, M.; Redl, H.; Reis, R. L.[Excerpt] Natural-based biomaterials are mainly constituted by proteins or polysaccharides which, under certain circumstances, may be recognized as natural host invaders. Starch-based scaffolds, produced by different methodologies, have been shown to hold adequate properties regarding mechanical performance and in vitro biocompatibility. This study aimed at evaluating the in vivo inflammatory response to starch...
Chitosan/soy-based membranes enhance wound reepithelialization in partial thick...
Santos, T. C.; Marques, A. P.; Silva, S. S.; Oliveira, Joaquim M.; Mano, J. F.; Castro, A. G.; van Griensven, M.; Redl, H.; Reis, R. L.[Excerpt] Chitosan-based biomaterials proved to have promising characteristics for wound dressing and skin regeneration. In the context of developing new natural-based biomaterials for these applications, chitosan and soybean-based biomaterials were proposed. These materials were shown to be non cytotoxic and to impair human leukocytes activation in vitro. Thus the goal of this study was to evaluate the in vivo...
A novel system for producing human recombinant BMP-2 and study of the growth fa...
Bessa, P. C.; Pedro, A. J.; Nobre, Alexandra; Dungl, P.; Banerjee, A.; Dopler, D.; Klösch, B.; Redl, H.; Casal, M.; Reis, R. L.Bone tissue engineering has been an increasing field of research during the last years. The ideal approach for a regenerative application would consist in the use of cells from the patient, scaffolding materials and differentiation growth factors. Bone morphogenetic protein-2 (BMP-2) is one such growth factors with a strong ability to induce new bone and cartilage formation and has been used as a powerful osteo...
Expression, purification and in vitro biological activity from human recombinan...
Bessa, Paulo C.; Pedro, A.; Nobre, Alexandra; Dungl, P.; Banerjee, A.; Dopler, D.; Klosch, B.; Redl, H.; Casal, Margarida; Reis, R. L.Bone tissue engineering has been an increasing field of research during the last years. The ideal approach for a regenerative application would consist in the use of cells from the patient, scaffolding materials and differentiation growth factors. Bone morphogenetic protein-2 (BMP-2) is one such growth factors with a strong ability to induce new bone and cartilage formation and has been used as a powerful osteo...