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Impact of ultrasound settings on lung vertical artefacts: an observational stud...

Leote, João; Gonçalves, Andreia; Fonseca, Júlia; Loução, Ricardo; Dias, Maria Hermínia Monteiro Brites; Ribeiro, Maria Inês; Meireles, Ricardo

The number of vertical artefacts (VAs) in lung ultrasound (LUS) impacts patients' clinical management. This study aimed to demonstrate the influence of ultrasound settings on the number of VAs in patients under invasive mechanical ventilation (IMV). Methods: Patients under IMV were recruited for LUS, including three breathing cycles with a motionless curvilinear probe on the thoracic region with the most VAs. T...


AI for the hemodynamic assessment of critically ill and surgical patients: focu...

Michard, Frederic; Mulder, Marijn P.; Gonzalez, Filipe; Sanfilippo, Filippo

Several artificial intelligence (AI)-driven tools have emerged for the hemodynamic evaluation of critically ill and surgical patients. This article provides an overview of current developments and potential clinical applications of machine learning (ML) for blood pressure measurements, hypotension prediction, hemodynamic profiling, and echocardiography. ML algorithms have shown promise in enabling continuous, n...


Total signal intensity of ultrasound laboratory vertical artifacts: a semi-quan...

Leote, Joao; Loução, Ricardo; Aguiar, Madalena; Tavares, Mariana; Ferreira, Paloma; Muxagata, Tiago; Guerreiro, Diana; Dias, Hermínia Brites

Quantitative approaches to improve lung ultrasound (LUS) vertical artifacts (VA) interpretation using total signal intensity (ITOT) are not widely available for clinical practice. In this study, we aimed to i) develop a mathematical algorithm to extract ITOT as a post-hoc LUS analysis and ii) confirm ITOT utility by conducting laboratory VA research using an in vitro model with different acoustic channels. The ...


Diastology in the intensive care unit: challenges for the assessment and future...

Gonzalez, Filipe; Santonocito, Cristina; Maybauer, Marc O.; Lopes, Luís Rocha; Almeida, Ana G.; Sanfilippo, Filippo

Myocardial dysfunction is common in patients admitted to the intensive care unit (ICU). Septic disease frequently results in cardiac dysfunction, and sepsis represents the most common cause of admission and death in the ICU. The association between left ventricular (LV) systolic dysfunction and mortality is not clear for critically ill patients. Conversely, LV diastolic dysfunction (DD) seems increasingly recog...


Underuse of reperfusion therapy with systemic thrombolysis in high-risk acute p...

Martinho, Mariana; Calé, Rita; Grade Santos, João; Rita Pereira, Ana; Alegria, Sofia; Ferreira, Filipa; José Loureiro, Maria; Judas, Tiago

Introduction: Reperfusion therapy is generally recommended in acute high-risk pulmonary embolism (HR-PE), but several population-based studies report that it is underused. Data on epidemiology, management and outcomes of HR-PE in Portugal are scarce. Objective: To determine the reperfusion rate in HR-PE patients, the reasons for non-reperfusion, and how it influences outcomes. Methods: In this retrospective coh...


Influence of ultrasound settings on laboratory vertical artifacts

Leote, Joao; Muxagata, Tiago; Guerreiro, Diana; Francisco, Cláudia; Dias, Hermínia Brites; Loução, Ricardo; Bacariza, Jacobo; Gonzalez, Filipe

Objective: The aim of the work described here was to analyze the relationship between the change in ultrasound (US) settings and the vertical artifacts' number, visual rating, and signal intensity METHODS: An in vitro phantom consisting of a damp sponge and gelatin mix was created to simulate vertical artifacts. Furthermore, several US parameters were changed sequentially (i.e., frequency, dynamic range, line d...


Machine learning for the real-time assessment of left ventricular ejection frac...

Varudo, Rita; Gonzalez, Filipe; Leote, João; Martins, Cristina; Bacariza, Jacobo; Fernandes, Antero; Michard, Frederic

Background: Machine learning algorithms have recently been developed to enable the automatic and real-time echocardiographic assessment of left ventricular ejection fraction (LVEF) and have not been evaluated in critically ill patients. Methods: Real-time LVEF was prospectively measured in 95 ICU patients with a machine learning algorithm installed on a cart-based ultrasound system. Real-time measurements taken...


Automation of sub-aortic velocity time integral measurements by transthoracic e...

Gonzalez, Filipe; Varudo, Rita; Leote, João; Martins, Cristina; Bacariza, Jacobo; Fernandes, Antero; Michard, Frederic

Point-of-care ultrasound techniques are increasingly used for the bedside assessment of cardiac function and haemodynamics in critically ill patients. The sub-aortic or left ventricular outflow tract velocity time integral (VTI) can be measured using pulsed-Doppler ultrasonography from a transthoracic apical 5-chamber view. Quantifying VTI is useful to discriminate between vasoplegic states (hypotension with no...


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