115 documents found, page 1 of 12

Gene expression association study in feline mammary carcinomas

Works on cancer-related genes expression using feline mammary carcinomas (FMCs) are scarce but crucial, not only to validate these tumours as models for human breast cancer studies but also to improve small animal practice. Here, the expression of the cancer-related genes TP53, CCND1, FUS, YBX1, PTBP1, c-MYC and PKM2 was evaluated by real-time RT-qPCR, in a population of FMCs clinically characterized and compar...

Book of Abstracts of the Xth International Symposium on Wild Fauna(ISoWiF 2017)

Motor coordination, activity, and fitness at 6 years of age relative to activit...

Health benefits of physical activity (PA) and physical fitness (PF) are reasonably well established, but tracking studies of PA and PF in childhood have not ordinarily considered the role of motor coordination. Objectives: To compare the growth status, gross motor coordination (GMC), PA and PF characteristics of children at 6 years of age relative to aerobic fitness (fit, unfit) and PA (active, sedentary) at 10...

ERBB2 in Cat Mammary Neoplasias Disclosed a Positive Correlation between RNA an...

Human ERBB2 is a proto-oncogene that codes for the erbB-2 epithelial growth factor receptor. In human breast cancer (HBC), erbB-2 protein overexpression has been repeatedly correlated with poor prognosis. In more recent works, underexpression of this gene has been described in HBC. Moreover, it is also recognised that oncogenes that are commonly amplified or deleted encompass point mutations, and some of these ...

Sequence variants and Haplotype analysis of Cat ERBB2 Gene: a survey on spontan...

Sequence variation and mRNA expression of the TWIST1 gene in cats with mammary ...

Defining the sister rat mammary tumor cell lines HH-16 cl.2/1 and HH-16.cl.4 as...

Cancer cell lines have been shown to be reliable tools in genetic studies of breast cancer, and the characterization of these lines indicates that they are good models for studying the biological mechanisms underlying this disease. Here, we describe the molecular cytogenetic/genetic characterization of two sister rat mammary tumor cell lines, HH-16 cl.2/1 and HH-16.cl.4, for the first time. Molecular cytogeneti...

Familial aggregation on trunkal fat: a study with Portuguese families

The aims of this study was to 1) identify the presence of indirect transmission of genetic factors between parents and children in two phenotypes of trunk fat, and 2) estimate the contribution of genetic and environmental factors responsible for phenotypic variation on relative trunk fat and absolute trunk fat. The sample consisted of 422 individuals from 107 Portuguese nuclear families. Trunk fat phenotypes we...

Analysis of ALU repeats for the identification of some polymorphic variants in ...

Touch-FISH: a capable protocol to study spontaneous abortions when cell culture...