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Investigating bioactive compounds in apple pomace: Potential to develop high ad...

Pascoalino, Liege; Finimundy, Tiane C.; Pires, Tânia C.S.P.; Pereira, Carla; Barros, Lillian; Ferreira, Isabel C.F.R.; Oliveira, Beatriz

This study investigates bioactive compounds in apple pomace (AP) obtained from Malus domestica varieties Granny Smith and Cripps Pink, emphasizing its potential for developing high-added-value products from industrial surplus. Regarding its chemical characterization, AP stood out for its high concentration of dietary fibers (7.1g/100g fw), polyunsaturated fatty acids (linoleic and oleic acids), α-tocopherol (0....

Date: 2025   |   Origin: Biblioteca Digital do IPB

Green and Innovative Extraction: Phenolic Profiles and Biological Activities of...

Pallarés, Noelia; Berrada, Houda; Ferrer, Emilia; Rached, Wahiba; Pinela, José; Mandim, Filipa; Pires, Tânia C.S.P.; Finimundy, Tiane C.

Underutilized plant species such as Asteriscus graveolens (Forssk.) Less., Haloxylon scoparium Pomel, and Ruta chalepensis L. have been historically valued in traditional medicine for their potential health benefits. These species present an untapped source of bioactive compounds with significant applications in the food and pharmaceutical industries, including the development of functional foods and additives....

Date: 2025   |   Origin: Biblioteca Digital do IPB

Authenticity and Bioactive Markers Search in the Phenolic‐Rich Extracts of Aste...

Garcia Perez, Pascual; Garcia‐Oliveira, Paula; Finimundy, Tiane C.; Pinela, José; Calhelha, Ricardo C.; Nenadić, Marija; Soković, Marina

The Asteraceae family has been of significant concern for ethnobotanical studies, thanks to its health-promoting properties linked to a plethora of bioactive compounds, among which phenolic compounds play a critical role. In this work, a workflow based on computational chemometrics was employed to assess the authenticity and biomarker search of five key Asteraceae species commonly employed in traditional medici...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Green extraction of anthocyanin from red cabbage waste using acid whey as a pro...

Oliveira, Jaine; Benvenutti, Laís; Albuquerque, Bianca R.; Finimundy, Tiane C.; Mandim, Filipa; Pires, Tânia C.S.P.; Pereira, Carla; Corrêa, Rúbia C.G.

The use of acid whey as a biological-based solvent may be an innovative and sustainable strategy to add value to agro-industrial by-products. This study assessed acid whey as a solvent for extracting anthocyanins from discarded red cabbage leaves. Methods such as Heating and Stirring Extraction (HSE), Ultrasound-Assisted Extraction (UAE), and Pressurized Liquid Extraction (PLE) were compared using acid whey or ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Exploring acorn shells: Phenolic composition and bioactive potential for sustai...

Mateus, Cristiano; Alonso-Esteban, José Ignacio; Finimundy, Tiane C.; Mandim, Filipa; Oliveira, Izamara; Babo, Pedro; Ferreira, Isabel C.F.R.

Pedunculate (Quercus robur L.), holm (Quercus rotundifolia Lam.), and cork (Quercus suber L.) oaks are abundant across the Portuguese landscape. This study aims to evaluate the phenolic composition and bioactivities of acorn shell samples and determine their potential as a functional compound source. In total, five acorn shell samples collected in different locations and from different species were analyzed: Q....

Date: 2025   |   Origin: Biblioteca Digital do IPB

The role of natural compounds in rat mammary cancer: the beneficial effects of ...

Azevedo, Tiago; Silva, Jessica; Peixoto, Francisco P.; Silvestre-Ferreira, Ana C.; Gama, Adelina; Seixas, Fernanda; Finimundy, Tiane C.; Barros, Lillian

Breast cancer is the most diagnosed cancer among women, and a leading cause of death worldwide. Santolina chamaecyparissus L. is a plant with multiple health benefits, including anticancer and anti-diabetic properties. This study aimed to assess the chemopreventive effects of S. chamaecyparissus aqueous extract (SCE) in an animal model of mammary cancer. A total of 28 four-week-old female Wistar rats were divid...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Chemical and Bioactive Evaluation of Essential Oils from Edible and Aromatic Me...

Sprea, Rafael M.; Caleja, Cristina; Finimundy, Tiane C.; Calhelha, Ricardo C.; Pires, Tânia C.S.P.; Amaral, Joana S.; Prieto Lage, Miguel A.

The Lamiaceae family, which includes several well-known aromatic plants, is scientifically relevant due to its essential oils (EOs). In this work, four EOs from Mediterranean species, namely Origanum vulgare L., Rosmarinus officinalis L., Salvia officinalis L., and Thymus vulgaris L., were evaluated for their volatile profiles and the biological activity in vitro to assess their potential use in the food and co...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Extraction of Bioactive Compounds from Rubus Idaeus Bioresidues: A Full Screeni...

Plasencia, Paula; Finimundy, Tiane C.; Carocho, Márcio; Calhelha, Ricardo C.; Añibarro-Ortega, Mikel; Pires, Tânia C.S.P.; Barreiro, Filomena

Purpose Rubus idaeus cultivation has boosted productivity due to its high nutritional value. In consequence, waste produc- tion increased. The discarded biomass, including leaves and aerial components, can be transformed into valuable functional ingredients for industrial applications, such as cosmetics. Studying their bioactivity potential is highly relevant. Methods According to the present idea, the research...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Cell Wall-Mediated Antifungal Activity of the Aqueous Extract of Hedera helix L...

Crisóstomo, Christina; Simões, Luara; Barros, Lillian; Finimundy, Tiane C.; Cunha, Ana; Oliveira, Rui P.

Cork oak forests have been declining due to fungal pathogens such as Diplodia corticola. However, the preventive fungicides against this fungus have restricted use due to the deleterious effects on human health and the environment, prompting the need for sustainable alternatives. Here, we describe the antifungal activity of an aqueous extract of Hedera helix L. leaves (HAE) against D. corticola and the possible...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Magnesium and manganese induced changes on chemical, nutritional, antioxidant a...

Oliveira, Izamara; Chrysargyris, Antonios; Finimundy, Tiane C.; Carocho, Márcio; Santos-Buelga, Celestino; Calhelha, Ricardo C.; Tzortzakis, Nikolaos

composition was determined using standard methods. Free sugars, fatty acids, organic acids, tocopherols, and phenolic compounds were analyzed using various HPLC and GC devises. The extract’s antimicrobial, antioxidant, cytotoxicity, and anti-inflammatory activity were assessed. The results indicated that Mg enrichment negatively affected plant growth and mineral accumulation but improved photosynthetic performa...

Date: 2024   |   Origin: Biblioteca Digital do IPB

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