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Bioactive and phenolic profiles in Pinus pinaster Bark : a comparative study of...

Barros, Diana; Alonso-Esteban, José Ignacio; Finimundy, Tiane C.; Pereira, Carla; Vaz, Josiana A.; Pereira-Pinto, Ricardo; Fernandes, Élia

This study conducted a comprehensive comparison of two green extraction methods, microwave-assisted extraction (MAE) and ultrasound-assisted extraction (UAE), for recovering bioactive phenolic compounds from Pinus pinaster bark. The goal was to valorize timber industry waste and enhance the value of by-products through the development of eco-friendly processes to extract phenolic compounds from Pinus pinaster A...

Date: 2026   |   Origin: Repositório Científico IPVC

Exploring the Chemopreventive and Antioxidant Effects of Spearmint Leaf Hydroet...

Jesus, Tiago M.; Azevedo, Tiago; Silva-Reis, Rita; Ferreira, Tiago; Nascimento-Gonçalves, Elisabete; Medeiros, Catarina; Ferreira, João; Gama, Adelina

Human papillomavirus (HPV) is the most common sexually transmitted infectious agent and, in cases of persistent infection, may cause cancer. This study evaluated the toxicological and antitumor properties of Mentha spicata extract (MSE) in KP14HPV16 mice, which carry HPV16 oncogenes. Thirty‑three female FVB/n mice (Mus musculus), including 17 HPV‑transgenic and 16 wild‑type (WT) mice, were divided into six grou...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Investigating bioactive compounds in apple pomace: Potential to develop high ad...

Pascoalino, Liege; Finimundy, Tiane C.; Pires, Tânia C.S.P.; Pereira, Carla; Barros, Lillian; Ferreira, Isabel C.F.R.; Oliveira, Beatriz

This study investigates bioactive compounds in apple pomace (AP) obtained from Malus domestica varieties Granny Smith and Cripps Pink, emphasizing its potential for developing high-added-value products from industrial surplus. Regarding its chemical characterization, AP stood out for its high concentration of dietary fibers (7.1g/100g fw), polyunsaturated fatty acids (linoleic and oleic acids), α-tocopherol (0....

Date: 2025   |   Origin: Biblioteca Digital do IPB

Valorization of Waste from Bell Pepper: Chemical Composition and Bioactive Pote...

Baessa, Jozias; Liberal, Ângela; Finimundy, Tiane C.; Stojković, Dejan; Mišić, Danijela; Pires, Tânia C.S.P.; Barros, Lillian; Fernandes, Ângela

Agri-food waste, especially in the fruit and vegetable sector, presents environmental and economic challenges. The bell pepper industry generates significant waste, offering potential for resource recovery within a circular economy. This study analyzed the nutritional and biochemical composition of waste from green, orange, and red bell peppers (Capsicum annuum L.) and evaluated the bioactive potential of hydro...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Green and Innovative Extraction: Phenolic Profiles and Biological Activities of...

Pallarés, Noelia; Berrada, Houda; Ferrer, Emilia; Rached, Wahiba; Pinela, José; Mandim, Filipa; Pires, Tânia C.S.P.; Finimundy, Tiane C.

Underutilized plant species such as Asteriscus graveolens (Forssk.) Less., Haloxylon scoparium Pomel, and Ruta chalepensis L. have been historically valued in traditional medicine for their potential health benefits. These species present an untapped source of bioactive compounds with significant applications in the food and pharmaceutical industries, including the development of functional foods and additives....

Date: 2025   |   Origin: Biblioteca Digital do IPB

Authenticity and Bioactive Markers Search in the Phenolic‐Rich Extracts of Aste...

Garcia Perez, Pascual; Garcia‐Oliveira, Paula; Finimundy, Tiane C.; Pinela, José; Calhelha, Ricardo C.; Nenadić, Marija; Soković, Marina

The Asteraceae family has been of significant concern for ethnobotanical studies, thanks to its health-promoting properties linked to a plethora of bioactive compounds, among which phenolic compounds play a critical role. In this work, a workflow based on computational chemometrics was employed to assess the authenticity and biomarker search of five key Asteraceae species commonly employed in traditional medici...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Nutritional and Biochemical Assessment of Edible Fruits From Angola's Native Flora

Rangel, Josefa; Liberal, Ângela; Pires, Tânia C.S.P.; Finimundy, Tiane C.; Barros, Lillian; Monteiro, Filipa; Romeiras, Maria M.; Fernandes, Ângela

Angola's native flora hides a wealth of underexplored edible fruits with significant nutritional and bioactive potential. This study provides a comprehensive evaluation of the physicochemical and bioactive potential of some less explored edible fruits from this country, namely Annona muricata, A. squamosa, A. senegalensis, A. boehmii, Dacryodes edulis, and Strychnos spinosa. Nutritional profiling revealed carbo...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Exploring acorn shells: Phenolic composition and bioactive potential for sustai...

Mateus, Cristiano; Alonso-Esteban, José Ignacio; Finimundy, Tiane C.; Mandim, Filipa; Oliveira, Izamara; Babo, Pedro; Ferreira, Isabel C.F.R.

Pedunculate (Quercus robur L.), holm (Quercus rotundifolia Lam.), and cork (Quercus suber L.) oaks are abundant across the Portuguese landscape. This study aims to evaluate the phenolic composition and bioactivities of acorn shell samples and determine their potential as a functional compound source. In total, five acorn shell samples collected in different locations and from different species were analyzed: Q....

Date: 2025   |   Origin: Biblioteca Digital do IPB

Green extraction of anthocyanin from red cabbage waste using acid whey as a pro...

Oliveira, Jaine; Benvenutti, Laís; Albuquerque, Bianca R.; Finimundy, Tiane C.; Mandim, Filipa; Pires, Tânia C.S.P.; Pereira, Carla; Corrêa, Rúbia C.G.

The use of acid whey as a biological-based solvent may be an innovative and sustainable strategy to add value to agro-industrial by-products. This study assessed acid whey as a solvent for extracting anthocyanins from discarded red cabbage leaves. Methods such as Heating and Stirring Extraction (HSE), Ultrasound-Assisted Extraction (UAE), and Pressurized Liquid Extraction (PLE) were compared using acid whey or ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Optimizing ultrasound-assisted extraction for enhanced yield of bioactive compo...

Plasencia, Paula; Carocho, Márcio; Finimundy, Tiane C.; Calhelha, Ricardo C.; Molina, Adriana K.; Pires, Tânia C.S.P.; Barreiro, Filomena

Due to the high nutritional value of berries, their extensive production has led to the accumulation of bioresidues. To leverage these residues, the distinct chemical composition, and functional properties of the leaves and other aerial parts can be used to produce high-value ingredients for cosmetics. Ultrasound-assisted extraction (UAE) is considered simple, fast, efficient, and more affordable than other tec...

Date: 2025   |   Origin: Biblioteca Digital do IPB

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