2 documents found, page 1 of 1
The real-life experience with cardiovascular complications in the first dose of...
Fragoso,Yara Dadalti; Arruda,Christian Cardoso; Arruda,Walter Oleschko; Brooks,Joseph Bruno Bidin; Damasceno,AlfredoFingolimod is a new and efficient treatment for multiple sclerosis (MS). The drug administration requires special attention to the first dose, since cardiovascular adverse events can be observed during the initial six hours of fingolimod ingestion. The present study consisted of a review of cardiovascular data on 180 patients with MS receiving the first dose of fingolimod. The rate of bradycardia in these patie...
Multiple sclerosis starting before the age of 18 years: the Brazilian experience
Fragoso,Yara Dadalti; Ferreira,Maria Lucia Brito; Morales,Nivea de Macedo Oliveira; Arruda,Walter Oleschko; Brooks,Joseph Bruno BidinMultiple sclerosis (MS) starting in childhood and adolescence poses a challenge for diagnosis and management of the disease. The aim of the present study was to assess the characteristics of early onset MS in Brazilian patients. Methods Retrospective data collection from specialized MS units. Results From 20 MS units in 11 Brazilian states, 117 cases of MS starting before the age of 18 years were collected. The...