3 documents found, page 1 of 1
Predictive and Therapeutic Implications of a Novel PLCγ1/SHP2-Driven Mechanism ...
Cruz-Duarte, Raquel; de Almeida, Cátia Rebelo; Negrão, Magda; Fernandes, Afonso; Borralho, Paula; Sobral, Daniel; Gallego-Paez, Lina M.; Machado, DanielP. Borralho reports grants from Roche and Novartis, as well as personal fees from Bayer and AstraZeneca outside the submitted work. D. Machado reports personal fees from Amgen and Merck outside the submitted work. H. Mansinho reports grants from AstraZeneca; nonfinancial support from AstraZeneca; and personal fees from Roche, Pfizer, Pierre Fabre, Incyte, BMS, Novartis, Amgen, Servier, Merck Serono, and Grunent...
Innate immune evasion revealed in a colorectal zebrafish xenograft model
Póvoa, Vanda; Rebelo de Almeida, Cátia; Maia-Gil, Mariana; Sobral, Daniel; Domingues, Micaela; Martinez-Lopez, Mayra; de Almeida Fuzeta, MiguelLISBOA-01-0145-FEDER-022170 CEECIND/ 02699/2017; Cancer immunoediting is a dynamic process of crosstalk between tumor cells and the immune system. Herein, we explore the fast zebrafish xenograft model to investigate the innate immune contribution to this process. Using multiple breast and colorectal cancer cell lines and zAvatars, we find that some are cleared (regressors) while others engraft (progressors) in ...
Object detection for automatic cancer cell counting in zebrafish xenografts
Albuquerque, Carina; Vanneschi, Leonardo; Henriques, Roberto; Castelli, Mauro; Póvoa, Vanda; Fior, Rita; Papanikolaou, NickolasAlbuquerque, C., Vanneschi, L., Henriques, R., Castelli, M., Póvoa, V., Fior, R., & Papanikolaou, N. (2021). Object detection for automatic cancer cell counting in zebrafish xenografts. PLoS ONE, 16(11), 1-28. [e0260609]. https://doi.org/10.1371/journal.pone.0260609 -----------------------------------------This work was supported by national funds through FCT (Fundaçâo para a Ciência e a Tecnologia), under proj...