3 documents found, page 1 of 1
Post-weaning exposure to high-fat diet induces kidney lipid accumulation and fu...
Fiorino, Patricia
Post-weaning exposure to high-fat diet induces kidney lipid accumulation and fu...
Muller, Cynthia R.; Leite, Ana Paula O.; Yokota, Rodrigo; Pereira, Renata O.; Americo, Anna Laura V.; Nascimento, Nilberto Robson Falcão doAim: We investigated the kidney morphofunctional consequences of high-fat diet intake since post-weaning in adult rats. Main Methods: Male Wistar rats were divided into two groups: ND (normal diet; n = 10) and HD (high-fat diet; n = 10). The high-fat diet was introduced post-weaned and animals were followed for 8 weeks. Key Findings: HD group did not change body weight gain even though food consumption has decr...
ACE gene dosage determines additional autonomic dysfunction and increases renal...
Moraes, Oscar Albuquerque de; Flues, Karin; Scapini, Kátia Bilhar; Mostarda, Cristiano; Evangelista, Fabiana de Sant’Anna; Rodrigues, BrunoOBJECTIVES: The present study aimed to investigate cardiovascular autonomic modulation and angiotensin II (Ang II) activity in diabetic mice that were genetically engineered to harbor two or three copies of the angiotensin-converting enzyme gene. METHODS: Diabetic and non-diabetic mice harboring 2 or 3 copies of the angiotensin-converting enzyme gene were used in the present study. Animals were divided into 4 g...