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Preservation of cytotoxic granule production in response to mycobacterial antig...

Arrym,Mauro Pedromonico; Alves,Paulo César Martins; Castelhano,Mariana Virginello; Mazzola,Taís Nitsch; Lemos,Renata Muller Banzato Pinto de

ABSTRACT Background: HIV infection harms adaptive cellular immunity mechanisms. Long-term virological control by combined antiretroviral therapy (cART) reduces the risk of mycobacterial infections. Thus, we aimed to study cellular responses to mycobacterial antigens in 20 HIV-infected adolescents with at least one year of virological control (HIV-RNA <40 copies/mL) and 20 healthy adolescents. Methods: We evalua...

Date: 2019   |   Origin: Oasisbr

Brazilian guidelines for the diagnosis and treatment of cystic fibrosis

Athanazio,Rodrigo Abensur; Silva Filho,Luiz Vicente Ribeiro Ferreira da; Vergara,Alberto Andrade; Ribeiro,Antônio Fernando; Riedi,Carlos Antônio

ABSTRACT Cystic fibrosis (CF) is an autosomal recessive genetic disorder characterized by dysfunction of the CFTR gene. It is a multisystem disease that most often affects White individuals. In recent decades, various advances in the diagnosis and treatment of CF have drastically changed the scenario, resulting in a significant increase in survival and quality of life. In Brazil, the current neonatal screening ...

Date: 2017   |   Origin: Oasisbr

Association of growth and nutritional parameters with pulmonary function in cys...

Mauch,Renan Marrichi; Kmit,Arthur Henrique Pezzo; Marson,Fernando Augusto de Lima; Levy,Carlos Emilio; Barros-Filho,Antonio de Azevedo

Abstract Objective: To review the literature addressing the relationship of growth and nutritional parameters with pulmonary function in pediatric patients with cystic fibrosis. Data source: A collection of articles published in the last 15 years in English, Portuguese and Spanish was made by research in electronic databases - PubMed, Cochrane, Medline, Lilacs and Scielo - using the keywords cystic fibrosis, gr...

Date: 2016   |   Origin: Oasisbr

Pseudomonas aeruginosa infection in patients with cystic fibrosis: scientific e...

Silva Filho,Luiz Vicente Ribeiro Ferreira da; Ferreira,Flavia de Aguiar; Reis,Francisco Jose Caldeira; Britto,Murilo Carlos Amorim de

Evidence-based techniques have been increasingly used in the creation of clinical guidelines and the development of recommendations for medical practice. The use of levels of evidence allows the reader to identify the quality of scientific information that supports the recommendations made by experts. The objective of this review was to address current concepts related to the clinical impact, diagnosis, and tre...

Date: 2013   |   Origin: Oasisbr

Taxa de infecção e sorotipos de Streptococcus agalactiae em amostras de recém-n...

Fiolo,Kateli; Zanardi,Cibele Esteves; Salvadego,Marizete; Bertuzzo,Carmem Silvia; Amaral,Eliana; Calil,Roseli; Levy,Carlos Emilio

OBJETIVO: Descrever os casos e o perfil microbiológico dos sorotipos de Streptococcus agalactiae provenientes de recém-nascidos em um Centro de Referência da Saúde da Mulher na cidade de Campinas, São Paulo, Brasil. MÉTODOS: Estudo transversal clínico-laboratorial realizado de janeiro de 2007 a dezembro de 2011. As cepas suspeitas, isoladas em amostras de sangue e líquor, foram identificadas a partir da hemólis...

Date: 2012   |   Origin: Oasisbr

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