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A mouse model reproducing the pathophysiology of neonatal group B streptococcal...
Andrade, EB; Magalhães, A; Puga, A; Costa, M; Bravo, J; Portugal, CC; Ribeiro, A; Correia-Neves, M; Faustino, A; Firon, A; Trieu-Cuot, P; Summavielle, TGroup B streptococcal (GBS) meningitis remains a devastating disease. The absence of an animal model reproducing the natural infectious process has limited our understanding of the disease and, consequently, delayed the development of effective treatments. We describe here a mouse model in which bacteria are transmitted to the offspring from vaginally colonised pregnant females, the natural route of infection. ...
Data: 2018
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Origem: Repositório Aberto da Universidade do Porto