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The contribution of second primary cancers to the mortality of patients with a ...

Gonçalves, E; Fontes, F; Rodrigues, JR; Calisto, R; Bento, MJ; Lunet, N; Morais, S

Purpose: Second primary cancers (SPCs) are estimated to affect nearly 5% of patients with breast cancer within 10 years of their diagnosis. This study aimed to estimate the contribution of SPCs to the mortality of patients with a breast first primary cancer (FPC). Methods: A population-based cohort of 17,210 patients with a breast FPC diagnosed between 2000 and 2010 was followed for SPCs (31/12/2015) and vital ...


Second primary cancers among females with a first primary breast cancer: a popu...

Gonçalves, E; Fontes, F; Rodrigues, JR; Calisto, R; Bento, MJ; Lunet, N; Morais, S

"Purpose To estimate the incidence rate of second primary cancers (SPCs) and the cumulative incidence of metachronous [diagnosed > 2 months after a first primary cancer (FPC)] SPCs in patients with a breast FPC, and to compare the incidence of SPC [overall, synchronous (≤ 2 months of the FPC) and metachronous] with that expected in the general female population. Methods A cohort of patients with a breast FPC fr...


The impact of the coronavirus disease 2019 pandemic on the diagnosis and treatm...

Morais, S; Antunes, L; Rodrigues, J; Fontes, F; Bento, MJ; Lunet, N

Objectives The coronavirus disease 2019 (COVID-19) pandemic has affected the availability of healthcare resources, and adjustments to cancer care have been necessary considering the risk of morbidity by COVID-19 and of cancer progression. This study aims to quantify the impact of the COVID-19 pandemic on the care of patients with cancer by comparing a period of 4 months after the outbreak began (2 March 2020) w...


Risk and Survival of Third Primary Cancers in a Population-Based Cohort of Brea...

Morais, S; Gonçalves, E; Fontes, F; Rodrigues, J; Calisto, R; Bento, MJ; Lunet, N

Introduction: The growing number of women diagnosed with breast cancer (BCa) together with high survival has resulted in an increasing population of survivors at risk of subsequent primary cancers. This study aimed to estimate the long-term risk and survival of third primary cancers (TPCs) among females with a first primary BCa. Methods: Breast first primary cancers (FPCs) from the Portuguese North Region Cance...


The impact of the COVID-19 pandemic on cancer screening

Morais, S; Antunes, L; Rodrigues, J; Fontes, F; Bento, MJ; Lunet, N

Letter to the editor


The impact of the COVID-19 pandemic on the short-term survival of patients with...

Morais, S; Antunes, L; Rodrigues, J; Fontes, F; Bento, MJ; Lunet, N

The COVID-19 pandemic led to potential delays in diagnosis and treatment of cancer patients, which may negatively affect the prognosis of these patients. Our study aimed to quantify the impact of COVID-19 on the short-term survival of cancer patients by comparing a period of 4 months after the outbreak began (2 March 2020) with an equal period from 2019. All cancer cases of the esophagus, stomach, colon and rec...


The effect of a gastric second primary cancer on the survival of patients with ...

Morais, S; Antunes, L; Bento, MJ; Lunet, N

Second primary cancers (SPCs) are an increasing concern among cancer survivors. In Northern Portugal, gastric cancer incidence is high, and alone corresponds to one in 10 SPCs diagnosed. Therefore, this study aims to estimate the contribution of gastric SPCs to the mortality of patients with a previous cancer. A population-based cohort of nongastric first primary cancer (FPC) patients from the North Region Canc...


Second primary gastric cancers in a region with an overall high risk of gastric...

Morais, S; Antunes, L; Bento, MJ; Lunet, N

Objective: To compare the incidence rates of gastric cancer among cancer survivors with those in the general population, and estimate the probability of a gastric second primary cancer being diagnosed 10 years after any other first primary cancer. Method: A cohort of first primary cancers (other than gastric) diagnosed in Northern Portugal between 2000 and 2006 (n=64,648) was followed until 31/12/2012 for gastr...


Risk and survival of third primary cancers in a population-based cohort of gast...

Morais, S; Antunes, L; Bento, MJ; Lunet, N

Background The growing number of gastric cancers together with improved survival resulted in an increasing population of survivors at risk of multiple primary cancers. Aims To estimate the 10-year risk and survival of third primary cancers (TPCs) among gastric first primary cancers (FPCs). Methods Gastric FPCs from the Portuguese North Region Cancer Registry, diagnosed in 2000-2006 (n = 7409), were followed for...


Second primary cancers and survival in patients with gastric cancer: associatio...

Morais, S; Castro, C; Antunes, L; Peleteiro, B; Bento, MJ; Lunet, N

To quantify the association between prediagnosis lifestyles with the risk of second primary cancers (SPCs) and survival of patients with gastric first primary cancer (FPC). We recruited 574 gastric patients from two major public hospitals in North Portugal (2001–2006). Smoking, alcohol and dietary habits in the year before FPC diagnosis were evaluated. Patients were followed up to 31 December 2011 for an SPC an...


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