1 document found, page 1 of 1
Sort by
Issue Date
ROCK1 in AgRP neurons regulates energy expenditure and locomotor activity in ma...
Huang, Hu; Lee, Seung Hwan; Ye, Chianping; Lima, Ines S.; Oh, Byung Chul; Lowell, Bradford B.; Zabolotny, Janice M.; Kim, Young BumNormal leptin signaling is essential for the maintenance of body weight homeostasis. Proopiomelanocortin- and agouti-related peptide (AgRP)-producing neurons play critical roles in regulating energy metabolism. Our recent work demonstrates that deletion of Rho-kinase 1 (ROCK1) in the AgRP neurons of mice increased body weight and adiposity. Here, we report that selective loss of ROCK1 in AgRP neurons caused a s...
Date: 2013
|
Origin: Repositório Institucional da UNL