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Next-Generation Sequencing of Hereditary Hemochromatosis-Related Genes: Novel L...

Faria, R; Silva, B; Silva, C; Loureiro, P; Queiroz, A; Fraga, S; Esteves, J; Mendes, D; Fleming, R; Vieira, L; Gonçalves, J; Faustino, P

Hereditary hemochromatosis (HH) is an autosomal recessive disorder characterized by excessive iron absorption resulting in pathologically increased body iron stores. It is typically associated with common HFE gene mutation (p.Cys282Tyr and p.His63Asp). However, in Southern European populations up to one third of HH patients do not carry the risk genotypes. This study aimed to explore the use of next-generation ...


Analysis of blood utilization in programmed surgery.

Oliveira, A; Fleming, R; Galvão, M

The purpose of this study is to analyse the crossmatched blood units for elective surgery and the real amount of transfused blood, the crossmatch:transfusion rate (C:T) which must be less than 2.5. As in other Blood Banks, the differences are more evident in the situations in which the need for blood is very small, the so called "Type and Screen".; The purpose of this study is to analyse the crossmatched blood ...

Date: 1997   |   Origin: Acta Médica Portuguesa

Autologous transfusion: 2 years of experience at the immuno-hemotherapy service...

Fleming, R; Nascimento, F; Madahil, A S

The results of a presurgical autologous blood transfusion program for two years are analysed. 1,709 patients were submitted to this program, but appraisable results were only obtained in 1,473. In 39.54% of these ones only autologous blood was used; 19.2% used both autologous and homologous blood; in 41.27% no blood was used; 23.8% of the blood for autologous transfusion was used as homologous. We conclude that...

Date: 1991   |   Origin: Acta Médica Portuguesa

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