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Mineral and Bone Metabolism Markers and Mortality in Diabetic Patients on Haemo...

Martín-Carro, B; Navarro-González, JF; Ortiz, A; Zoccali, C; Floege, J; Ferreira, MA; Gorriz-Teruel, JL; Carrillo-López, N; Panizo, S; Locatelli, F

Background: Diabetic patients on haemodialysis have a higher risk of mortality than non-diabetic patients. The aim of this COSMOS (Current management of secondary hyperparathyroidism: a multicentre observational study) analysis was to assess whether bone and mineral laboratory values [calcium, phosphorus and parathyroid hormone (PTH)] contribute to this risk. Methods: COSMOS is a multicentre, open-cohort, 3-yea...


Risk of Hospitalization Associated With Body Mass Index and Weight Changes Amon...

Carrero, J; Rodríguez-Cabezas, I; Qureshi, A; Floege, J; Ketteler, M; London, G; Locatelli, F; Memmos, D; Goldsmith, D; Ferreira, A; Nagy, J; Teplan, V

The impact of body mass index (BMI) and body weight on hospitalization rates in haemodialysis patients is unknown. This study hypothesizes that being either underweight or obese is associated with a higher hospitalization rate. Observational study of 6296 European haemodialysis patients with prospective data collection and follow-up every six months for three years (COSMOS study). The risk of being hospitalized...


Improvement of Mineral and Bone Metabolism Markers Is Associated with Better Su...

Fernández-Martín, JL; Martínez-Camblor, P; Dionisi, MP; Floege, J; Ketteler, M; London, G; Locatelli, F; Gorriz, JL; Rutkowski, B; Ferreira, A; Bos, WJ

BACKGROUND: Abnormalities in serum phosphorus, calcium and parathyroid hormone (PTH) have been associated with poor survival in haemodialysis patients. This COSMOS (Current management Of Secondary hyperparathyroidism: a Multicentre Observational Study) analysis assesses the association of high and low serum phosphorus, calcium and PTH with a relative risk of mortality. Furthermore, the impact of changes in thes...


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