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PREPARATION AND CHARACTERIZATION OF NANOEMULSION CONTAINING A NATURAL NAPHTHOQU...
Rodrigues,Fernando V. S.; Diniz,Laerte S.; Sousa,Rosa M. G.; Honorato,Thalita D.; Simão,Daniele O.; Araújo,Cleônia R. M.; Gonçalves,Talita M.Natural naphthoquinones such as lapachol (Lp) have demonstrated promising biological activities. However, these quinones present low systemic biodisponibility due to its poor aqueous solubility. To overcome this problem, nanoemulsions (NE) formed by oily core are able to incorporate hydrophobic molecules thus enabling them to be dispersed into an aqueous phase. The present study reports the development, charact...
Date: 2018
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Origin: Oasisbr