19 documents found, page 1 of 2
Choroidal Vascular Impairment in Intermediate Age-Related Macular Degeneration
Flores, R; Carneiro, A; Neri, G; Fradinho, A; Quenderra, B; Barata, MJ; Tenreiro, S; Seabra, MAge-related macular degeneration (AMD) is a multifactorial disease, whose complete pathogenesis is still unclear. Local hemodynamics may play a crucial role in its manifestation and progression. To evaluate choroidal and retinal vascular parameters, a total of 134 eyes were analyzed, 100 with intermediate AMD and 34 age matched healthy controls. 131 eyes of 104 patients were eligible for complete image assessme...
Retinal Progression Biomarkers of Early and Intermediate Age-Related Macular De...
Flores, R; Carneiro, A; Tenreiro, S; Seabra, MCEarly and intermediate AMD patients represent a heterogeneous population with an important but variable risk of progression to more advanced stages of the disease. The five-year progression from early and intermediate AMD to late disease is known to range from 0.4% to 53%. This wide variation explains the particular interest in searching predictive AMD biomarkers. Clinical parameters such as drusen size, presen...
Guidelines for the Management of Center-Involving Diabetic Macular Edema: Treat...
Figueira, J; Henriques, J; Carneiro, A; Marques-Neves, C; Flores, R; Castro-Sousa, JP; Meireles, A; Gomes, N; Nascimento, J; Amaro, M; Silva, RDiabetic macular edema (DME) is the main cause of visual impairment associated with diabetic retinopathy (DR) and macular laser, during approximately three decades, and was the single treatment option. More recently, intravitreous injections of anti-angiogenics and corticosteroids modified the treatment paradigm associated with significant vision improvements. Nevertheless, not all patients respond satisfactori...
Chronic Lacrimal Canaliculitis - the Answer to a Three-Year History of Red Eye
Basílio, AL; Cabugueira, A; Borges, B; Flores, R; Amaro, A; Magriço, AChronic lacrimal canaliculitis is a rare infection of the lacrimal system, and can lead to misdiagnosis due to its overlapping presentation to other common entities. The authors report a case of lacrimal canaliculitis with a three-year history of recurrent unilateral red eye and mucopurulent discharge. Here, we describe the clinical course, surgical details, and microbial analysis of canaliculitis infection.
XEN® Implant and Trabeculectomy Medium-Term Quality of Life Assessment and Comp...
Basílio, AL; Moura-Coelho, N; Passos, I; Sá Cardoso, M; Domingues, I; Reina, M; Flores, R; Gomes, TAIM: To evaluate and compare the quality of life of patients submitted to XEN® implant or trabeculectomy and the relationship with potentially involved variables. METHODS: A cross-sectional study of patients with advanced open-angle glaucoma who underwent implantation of XEN® (group 1) and trabeculectomy (group 2) between October 2015 and February 2017. The studied variables were: age, gender, follow-up time, n...
Real-world outcomes of anti-VEGF treatment for retinal vein occlusion in Portugal
Vaz-Pereira, S; Marques, I; Matias, JG; Mira, F; Ribeiro, L; Flores, RPURPOSE: Retinal vein occlusion (RVO) is an important cause of visual disability in the modern world. We aim to evaluate the real-world outcomes of patients with RVO treated with anti-vascular endothelial growth factor (VEGF) in Portugal. METHODS: We performed a retrospective, observational, multicenter study including 8 centers across Portugal and 200 patients treated with either ranibizumab or bevacizumab. Da...
A Retrospective Analysis of the Real-Life Utilization of Ranibizumab in Patient...
Silva, R; Goncalves, C; Meireles, A; Teixeira, C; Rosa, P; Monteiro-Grillo, M; Canelas, J; Carneiro, A; Flores, RINTRODUCTION: Anti-vascular endothelial growth factor therapy has revolutionized the treatment of wet age-related macular degeneration; however, it is important to monitor actual use of ranibizumab and related treatment outcomes in routine practice. MATERIAL AND METHODS: This was a retrospective, observational study to monitor the 2-year outcomes following ranibizumab treatment for wet age-related macular degen...
Real-World Outcomes of Anti-VEGF Treatment for Retinal Vein Occlusion in Portugal
Vaz-Pereira, S; Marques, IP; Matias, J; Mira, F; Ribeiro, L; Flores, RPurpose: Retinal vein occlusion (RVO) is an important cause of visual disability in the modern world. We aim to evaluate the real-world outcomes of patients with RVO treated with anti-vascular endothelial growth factor (VEGF) in Portugal. Methods: We performed a retrospective, observational, multicenter study including 8 centers across Portugal and 200 patients treated with either ranibizumab or bevacizumab. Da...
Parâmetros Morfológicos no SD-OCT em Doentes com Degeneração Macular da Idade A...
Noronha, M; Borges, B; Cabugueira, A; Carvalho, B; Gomes, T; Marques, M; Flores, RObjectivo: Estudar a evolução dos parâmetros quantitativos e qualitativos obtidos na tomografia de coerência óptica spectral domain (SD-OCT) num sub-grupo de doentes com degeneração macular da idade (DMI) sujeitos a injecções intravítreas (IV) de bevacizumab. Procurou-se também verificar se estes parâmetros poderão funcionar como factores de prognóstico da acuidade visual (AV) pós- terapêutica com IV de bevaciz...
Correlação entre Espessura Macular e Camada de Fibras Nervosas Peripapilar no G...
Cabugueira, A; Vicente, A; Lemos, V; Anjos, R; Rosa, R; Flores, R; Gomes, T; Reina, MIntrodução: Os autores pretendem analisar a espessura macular e a camada de fibras nervosas peripapilar (CFN) em doentes com glaucoma inicial e com o diagnóstico de hipertensão ocular (HTO). Também propõem um modelo de correspondência da espessura macular de uma dada região do hemisfério superior com a CFN temporal superior (TS) e do hemisfério inferior com a CFN temporal inferior (TI) no glaucoma inicial. Mate...