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HepatoPredict Accurately Selects Hepatocellular Carcinoma Patients for Liver Tr...

Andrade, Rita; Perez-Rojas, Judith; da Silva, Sílvia Gomes; Miskinyte, Migla; Quaresma, Margarida C; Frazão, Laura P; Peixoto, Carolina

Background/objectives: Hepatocellular carcinoma (HCC) is a major cause of cancer-related deaths rising worldwide. This is leading to an increased demand for liver transplantation (LT), the most effective treatment for HCC in its initial stages. However, current patient selection criteria are limited in predicting recurrence and raise ethical concerns about equitable access to care. This study aims to enhance pa...


HepatoPredict Accurately Selects Hepatocellular Carcinoma Patients for Liver Tr...

Andrade, Rita; Pérez, Judith; da Silva, Sílvia Gomes; Miskinyte, Migla; Quaresma, Margarida C.; Frazão, Laura P.; Peixoto, Carolina; Cubells, Almudena

Publisher Copyright: © 2025 by the authors.; Background/Objectives: Hepatocellular carcinoma (HCC) is a major cause of cancer-related deaths rising worldwide. This is leading to an increased demand for liver transplantation (LT), the most effective treatment for HCC in its initial stages. However, current patient selection criteria are limited in predicting recurrence and raise ethical concerns about equitable ...


High-value molecules from Cynara cardunculus L.

Folgado, André

"Cynara cardunculus L. also known as cardoon or thistle flower is a plant endemic to the Mediterranean basin region. In some countries, the flower of cardoon is harvested and used as milk clotting agent in traditional cheese manufacturing. This process occurs due to the activity of aspartic proteases (APs) present in the flower, known as cardosins and cyprosins. Despite this economic importance, the use of card...


O cardo e a indústria de queijo: ferramentas biotecnológicas para a produção de...

Folgado, André; Abranches, Rita

Em Portugal, como noutros países da bacia mediterrânica, a planta de cardo (Cynara cardunculus L.) tem sido utilizada desde tempos antigos para diversas aplicações nas áreas alimentar e da saúde. Em particular, no caso da produção artesanal de queijo de cabra e ovelha, a flor do cardo tem sido usada, muitas vezes de uma forma empírica, no processo de coagulação do leite. Esta utilização deve-se ao facto da flor...

Date: 2019   |   Origin: Revista de Ciências Agrárias

Comprehensive analysis of the cork oak (Quercus suber) transcriptome involved i...

Usié, Ana; Simões, Fernanda; Barbosa, Pedro; Meireles, Brígida; Chaves, Inês; Gonçalves, Sónia; Folgado, André; Almeida, Maria Helena; Matos, José

Cork oaks show a high capacity of bud sprouting as a response to injury, which is important for species survival when dealing with external factors, such as drought or fires. The characterization of the cork oak transcriptome involved in the different stages of bud sprouting is essential to understanding the mechanisms involved in these processes. In this study, the transcriptional profile of different stages o...


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