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Transcriptomic-Based Classification Identifies Prognostic Subtypes and Therapeu...

Esperança-Martins, Miguel; Vasques, Hugo; Ravasqueira, Manuel Sokolov; Lemos, Maria Manuel; Fonseca, Filipa; Coutinho, Diogo; López, Jorge Antonio

Funding Information: This research was sponsored by F.Hoffmann-LaRoche AG and by Foundation Medicine Inc. under the RNA LDT Research Programme. Funding Information: We would like to thank F.Hoffmann-LaRoche AG and Foundation Medicine Inc. for providing the FoundationOneCDx and FoundationOneRNA assays, and for all the technical support, specifically during the transfer of the sequencing data via the safe platfor...


Succinate Dehydrogenase B (SDHB) Overexpression with Enzymatic Dysfunction Defi...

Esperança-Martins, Miguel; Vasques, Hugo; Ravasqueira, Manuel Sokolov; Santos, Filipa; Fonseca, Filipa; Queiroz, António Syder; Boavida, João

Publisher Copyright: ©2025 The Authors; Published by the American Association for Cancer Research.; Undifferentiated pleomorphic sarcoma (UPS) remains one of the most clinically aggressive and poorly characterized soft-tissue sarcoma subtypes. To uncover distinctive molecular traits for UPS, a multiomics analysis of UPS compared with leiomyosarcoma (LMS) and liposarcoma (LPS) was performed. Transcriptomic profi...


Heterogeneity in physician's job preferences in a dual practice context

Pestana, Joana; Frutuoso, João; Costa, Eduardo; Fonseca, Filipa

Publisher Copyright: © 2023 The Authors; Many countries are facing challenges in recruiting and retaining physicians, particularly in regions where the public and private sectors compete for doctors. Understanding the factors influencing physicians’ job choices can help inform policies aimed at attracting and retaining this valuable workforce. This study aims to elicit the strength of physicians' preferences re...


Handling of fresh vegetables

Salamandane, Cátia; Fonseca, Filipa; Afonso, Sónia; Lobo, Maria Luisa; Antunes, Francisco; Matos, Olga

In developing countries, markets are the main supply of horticultural products to populations, but this can pose a public health challenge due to the risk of the fecal-oral transmission of gut pathogens. This transmission is strongly associated with inadequate public sanitation or low standards of personal and domestic hygiene, and their prevalence can cause gastrointestinal diseases, which are the third leadin...


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