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Dectin-1-Mediated Production of Pro-Inflammatory Cytokines Induced by Yeast β-G...

Pedro, ARV; Lima, T; Fróis-Martins, R; Leal, B; Ramos, IC; Martins, EG; Cabrita, ARJ; Fonseca, AJM; Maia, MRG; Vilanova, M; Correia, A

Yeast-derived products containing β-glucans have long been used as feed supplements in domesticated animals in an attempt to increase immunity. β-glucans are mainly recognized by the cell surface receptor CLEC7A, also designated Dectin-1. Although the immune mechanisms elicited through Dectin-1 activation have been studied in detail in mice and humans, they are poorly understood in other species. Here, we evalu...


Effect of zinc source and exogenous enzymes supplementation on zinc status in d...

Pereira, AM; Guedes, M; Matos, E; Pinto, E; Almeida, AA; Segundo, MA; Correia, A; Vilanova, M; Fonseca, AJM; Cabrita, ARJ

Zinc is an essential element, a cofactor of many enzymes, and performs catalytic, structural and regulatory functions. Once in the gastrointestinal tract, zinc can interact with food constituents. Phytic acid, the major phosphorus storage in plants, limits zinc availability from animal feeds due to the formation of insoluble complexes with phytates. This study tested the effect of supplemental zinc source (zinc...


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