6 documents found, page 1 of 1
Unraveling Enterococcus susceptibility to quaternary ammonium compounds: genes,...
Pereira, AP; Antunes, Patrícia; Bierge, P; Willems, RJL; Corander, J; Coque, TM; Pich, OQ; Peixe, L.; Freitas, AR; Novais, CarlaQuaternary ammonium compounds (QACs) have been extensively used in the community, healthcare facilities, and food chain, in concentrations between 20 and 30,000 mg/L. Enterococcus faecalis and Enterococcus faecium are ubiquitous in these settings and are recognized as nosocomial pathogens worldwide, but QACs' activity against strains from diverse epidemiological and genomic backgrounds remained largely unexplor...
Evolution of chlorhexidine susceptibility and of the EfrEF operon among Enteroc...
Pereira, AP; Antunes, Patrícia; Willems, R; Corander, J; Coque, TM; Peixe, L.; Freitas, A.R.; Novais, CarlaABSTRACTChlorhexidine (CHX) is widely used to control the spread of pathogens (e.g. human/animal clinical settings, ambulatory care, food industry). E. faecalis, a major nosocomial pathogen, is broadly distributed in diverse hosts and environments facilitating its exposure to CHX over the years. Nevertheless, CHX activity against E. faecalisis understudied. Our goal was to assess CHX activity and the variabilit...
Evolution of Chlorhexidine Susceptibility and of the EfrEF Operon among Enteroc...
Pereira, AP; Antunes, Patrícia; Willems, R; Corander, J; Coque, TM; Peixe, L.; Freitas, AR; Novais, C.Chlorhexidine (CHX) is widely used to control the spread of pathogens (e.g., human/animal clinical settings, ambulatory care, food industry). Enterococcus faecalis, a major nosocomial pathogen, is broadly distributed in diverse hosts and environments facilitating its exposure to CHX over the years. Nevertheless, CHX activity against E. faecalis is understudied. Our goal was to assess CHX activity and the variab...
Diversity of metal and antibiotic resistance genes in Enterococcus spp. from th...
Rebelo, A; Mourao, J; Freitas, AR; Duarte, B; Silveira, E; Sanchez Valenzuela, A; Agostinho Almeida; Baquero, F; Coque, TM; Peixe, L.; Antunes, PatríciaArsenic (As), mercury (Hg), and copper (Cu) are among the major historical and contemporary metal pollutants linked to global anthropogenic activities. Enterococcus have been considered indicators of fecal pollution and antibiotic resistance for years, but its largely underexplored metallome precludes understanding their role as metal pollution bioindicators as well. Our goal was to determine the occurrence, di...
2CS-CHXT Operon Signature of Chlorhexidine Tolerance among Enterococcus faecium...
Duarte, B; Pereira, AP; Freitas, AR; Coque, TM; Hammerum, AM; Hasman, H; Antunes, Patrícia; Peixe, L.; Novais, CarlaChlorhexidine (CHX) is a broad-spectrum antiseptic widely used in community and clinical contexts for many years that has recently acquired higher relevance in nosocomial infection control worldwide. Despite this, CHX tolerance among Enterococcus faecium bacteria, representing one of the leading agents causing nosocomial infections, has been poorly understood. This study provides new phenotypic and molecular da...
Water supply and feed as sources of antimicrobial-resistant Enterococcus spp. i...
Novais, Carla; Campos, J; Freitas, AR; Barros, M; Silveira, E; Coque, TM; Antunes, Patrícia; Luisa PeixeThe role of European fish farms in the spread of antimicrobial-resistance in the environment and food chain, as well as possible sources of their contamination by clinically relevant antimicrobial-resistance bacteria is scarcely known. This study aimed to assess the contribution of Portuguese rural trout farms on dispersion of Enterococcus with antimicrobial-resistance and putative virulence genes in the enviro...