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Programmes Addressed to Informal Caregivers’ Needs: A Systematic Literature Rev...

Gemito, L; Alves, Elisabete; Moreira, J; Marques, MF; Caldeira, E; Ferreira, R; Bico, I; Pinho, L; Fonseca, C; Sousa, L; Lopes, M

Background: Addressing informal caregivers' needs is essential for ensuring quality healthcare and promoting citizen-centred care. This systematic review assessed current knowledge about programmes aimed at meeting the needs of informal caregivers of adults who are dependent on others for daily life activities. Methods: Following the PRISMA guidelines, the electronic databases EBSCOhost Research Platform, MEDLI...


Health-related outcomes of structured home-based rehabilitation programs among ...

Alves, Elisabete; Gonçalves, C; Oliveira, H; Ribeiro, R; Fonseca, C

The aging population reveals the need to develop self-care interventions that promote autonomy and well-being. The current systematic review aimed to assess the association between the implementation of structured home-based rehabilitation programs to promote self-care in older adults and health-related outcomes among people aged 60 years or older. Following the Preferred Reporting Items for Systematic Reviews ...


Moderate intensity treadmill exercise influences the immune system and prostate...

Nascimento-Gonçalves, E; Seixas, F; Palmeira, C; Martins, G; Fonseca, C; Duarte, JA; Faustino-Rocha, Ana I; Colaço, B; Pires, MJ; Neuparth, MJ

Material & Methods: Fifty-five male Wistar rats were divided into: control sedentary (SED+CONT; n=10), control exercised (EX+CONT; n=10), induced sedentary (SED+PCa; n=15), and induced exercised (EX+PCa; n=20). Exercised animals were trained in a treadmill, for 53 weeks. PCa induction consisted of flutamide and N-methyl-N-nitrosourea administration, followed by testosterone propionate implants. At sacrifice, pr...


Immune system and prostate signalome in a rat model of prostate cancer: influen...

Nascimento-Gonçalves, E; Seixas, F; Palmeira, C; Martins, G; Fonseca, C; Duarte, JA; Faustino-Rocha, Ana I; Colaço, B; Pires, MJ; Neuparth, MJ

Immune system and prostate signalome in a rat model of prostate cancer: influence of lifelong exercise training


Unveiling the role of moderate exercise training in immune system and prostate ...

Nascimento-Gonçalves, E; Seixas, F; Palmeira, C; Martins, G; Fonseca, C; Duarte, JA; Faustino-Rocha, Ana I; Colaço, B; Pires, MJ; Neuparth, MJ

Background: Prostate cancer (PCa) is among the most prevalent cancers worldwide. This work aimed to under- stand the effects of exercise training in a rat model of PCa chemically and hormonally-induced. Material and Methods: Fifty-five male Wistar rats were divided into: control sedentary (SED+CONT; n=10), control exercised (EX+CONT; n=10), induced seden- tary (SED+PCa; n = 15) and induced exercised (EX+PCa; n=...


Moderate intensity treadmill exercise influences the immune system and prostate...

Nascimento-Gonçalves, E; Seixas, F; Palmeira, C; Martins, G; Fonseca, C; Duarte, JA; Faustino-Rocha, Ana I; Colaço, B; Pires, MJ; Neuparth, MJ

MODERATE INTENSITY TREADMILL EXERCISE INFLUENCES THE IMMUNE SYSTEM AND PROSTATE SIGNALOME IN A RAT MODEL OF PROSTATE CANCER


Immune system and prostate signalome in a rat model of prostate cancer: influen...

Nascimento-Gonçalves, E; Seixas, F; Palmeira, C; Martins, G; Fonseca, C; Duarte, JA; Faustino-Rocha, Ana I; Colaço, B; Pires, MJ; Neuparth, MJ

Immune system and prostate signalome in a rat model of prostate cancer: influence of lifelong exercise training


The 2021 Portuguese Society of Ophthalmology Joint Guidelines with Paediatric R...

Leal, I; Miranda, V; Fonseca, C; Barbosa-Breda, J; Cordeiro Sousa, D; Mesquita-Marques, P; Araújo, J; Silva, MI; Pedrosa, AC; Palmares, J; Furtado, MJ

Aim: To develop the first Ophthalmology joint guidelines with Paediatric Rheumatology with recommendations on the screening, monitoring and medical treatment of juvenile idiopathic arthritis-associated uveitis (JIA-U), endorsed by the Portuguese Society of Ophthalmology (SPO). Methods: A systematic literature review was conducted to include publications up to July 14th 2020, with no language restrictions, in or...


Circulating Tumor DNA Tracking Through Driver Mutations as a Liquid Biopsy-Base...

Bustamante, P; Tsering, T; Coblentz, J; Mastromonaco, C; Abdouh, M; Fonseca, C; Proença, RP; Blanchard, N; Dugé, CL; Andujar, RAS; Youhnovska, E

Background: Uveal melanoma (UM) is the most common intraocular tumor in adults. Despite good primary tumor control, up to 50% of patients develop metastasis, which is lethal. UM often presents asymptomatically and is usually diagnosed by clinical examination and imaging, making it one of the few cancer types diagnosed without a biopsy. Hence, alternative diagnostic tools are needed. Circulating tumor DNA (ctDNA...


Hyperkalemia and management of renin-angiotensin-aldosterone system inhibitors ...

Fonseca, C; Brito, D; Branco, P; Frazão, JM; Silva-Cardoso, J; Bettencourt, P

Introduction and Objectives: Renin-angiotensin-aldosterone system inhibitors (RAASi) are the cornerstone of treatment of heart failure with reduced ejection fraction (HFrEF). RAASi optimization in real-life care is challenged by hyperkalemia, a potentially fatal adverse event, which can necessitate downtitration or discontinuation of RAASi and negatively impact survival in HFrEF. The literature on this problem ...


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