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A Portuguese expert panel position paper on the management of heart failure wit...

Silva-Cardoso, José; Moreira, Emília; Melo, Rachel Tavares de; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mário; Gavina, Cristina; Moura, Brenda

In Portugal, a 15.2% prevalence of heart failure with preserved ejection fraction (HFpEF) was recently identified among those aged ≥50 years. HFpEF represents 90% of Portuguese heart failure patients. HFpEF management in Portugal is challenging due to patient heterogeneity, diagnostic and therapeutic complexity, and organizational constraints on the healthcare system. Considering the above, a panel of Portugues...


A Portuguese expert panel position paper on the management of heart failure wit...

Silva-Cardoso, José; Moreira, Emília; Melo, Rachel Tavares de; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mário; Gavina, Cristina; Moura, Brenda

Heart failure (HF) with preserved ejection fraction (HFpEF) affects more than 50% of HF patients worldwide, and more than 70% of HF patients aged over 65. This is a complex syndrome with a clinically heterogeneous presentation and a multifactorial pathophysiology, both of which make its diagnosis and treatment challenging. A Portuguese HF expert panel convened to address HFpEF pathophysiology and therapy, as we...


Correction to: worsening heart failure: progress, pitfalls, and perspectives (H...

Fonseca, Cândida; Baptista, Rui; Franco, Fátima; Moura, Brenda; Pimenta, Joana; Sarmento, Pedro Moraes; Cardoso, José Silva; Brito, Dulce

The order of the authors' first and last names was reversed in the original publication. The correct author names are as follows: Incorrect Author List: Fonseca Cândida · Baptista Rui · Franco Fátima · Moura Brenda · Pimenta Joana · Pedro Moraes Sarmento · Silva Cardoso José · Brito Dulce Correct Author List: Cândida Fonseca · Rui Baptista · Fátima Franco · Brenda Moura · Joana Pimenta · Pedro Moraes Sarmento ·...


A Portuguese Expert Panel Position Paper on the Management of Heart Failure wit...

Silva-Cardoso, José; Moreira, Emília; Tavares de Melo, Rachel; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mário; Gavina, Cristina; Moura, Brenda

In Portugal, a 15.2% prevalence of heart failure with preserved ejection fraction (HFpEF) was recently identified among those aged ≥50 years. HFpEF represents 90% of Portuguese heart failure patients. HFpEF management in Portugal is challenging due to patient heterogeneity, diagnostic and therapeutic complexity, and organizational constraints on the healthcare system. Considering the above, a panel of Portugues...


Myocardial Performance Improvement After Iron Replacement in Heart Failure Pati...

Ramos, Raúl; Ras Jimenez, Maria Del Mar; Basalo Carbajales, María Del Carmen; Jovells Vaqué, Sílvia; GARCIA-PINILLA, JOSE MANUEL; Cobo-Marcos, Marta

Funding Information: The IRON-PATH II study was sponsored by CSL Vifor with coordination by Bellvitge Biomedical Research Institute (IDIBELL). The sponsor did not participate in the design of this study nor data analysis. An independent data and safety monitoring committee reviewed the data every 6 months. This study was approved by the local ethics committees for clinical research at each participating center ...


Factors Associated with Clinically Important Changes in Quality of Life of Hear...

Marques, Irene; Severo, Milton; Pinto, António; Fonseca, Cândida; Carvalho, Henrique Cyrne

Funding Information: The APC was funded by a PhD scholarship granted to I.M.: Bolsa CHUdSA 2023\u2014financed by Fundo para a Investiga\u00E7\u00E3o e Desenvolvimento do Centro Hospitalar Universit\u00E1rio de Santo Ant\u00F3nio. Publisher Copyright: © 2025 by the authors.; Background/Objectives: We aimed to identify the factors associated with clinically important changes in quality of life (QoL) of real-world...


Quality of life score association with other patient-reported outcomes

Marques, Irene; Viamonte, Sofia; Severo, Milton; Gomes Pinto, António; Fonseca, Cândida; Carvalho, Henrique Cyrne

Publisher Copyright: © 2025 Sociedade Portuguesa de Cardiologia; Introduction and objectives: Pragmatic validated instruments are needed to assess quality of life (QoL) in the real-world care of heart failure (HF) patients. This study aimed to validate the Minnesota Living with Heart Failure Questionnaire (MLHFQ) in European Portuguese and to search for associations with other patient-reported outcomes (PROs). ...


Serum Growth Differentiation Factor 15 (GDF15) Levels Reflect Ischemic Etiology...

Tajes, Marta; Ras-Jiménez, Maria del Mar; Girona, Josefa; Ramos-Polo, Raúl; Guardiola, Montse; García-Pinilla, José Manuel; Ribalta, Josep

Funding Information: This research was funded by CIBER (Consorcio Centro de Investigaci\u00F3n Biom\u00E9dica en Red) (CB07/08/0028) and the Department of Research and Universities of the Generalitat of Catalonia (SGR-00815). Publisher Copyright: © 2025 by the authors.; Heart failure (HF), particularly of an ischemic etiology, is steadily increasing worldwide. Non-anemic iron deficiency (ID) is highly prevalent...


Worsening heart failure: progress, pitfalls, and perspectives

Fonseca, Cândida; Baptista, Rui; Franco, Fátima; Moura, Brenda; Pimenta, Joana; Moraes Sarmento, Pedro; Cardoso, José Silva; Brito, Dulce

For most patients with chronic heart failure (HF), the clinical course of the disease includes periods of apparent clinical stability punctuated by episodes of clinical deterioration with worsening signs and symptoms, a condition referred to as worsening heart failure (WHF). Over time, episodes of WHF may become more frequent, and patients may enter a cycle of recurrent events associated with deterioration in t...


A Portuguese expert panel position paper on the management of heart failure wit...

Silva-Cardoso, José; Moreira, Emília; Tavares de Melo, Rachel; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mario; Gavina, Cristina; Moura, Brenda

Heart failure (HF) with preserved ejection fraction (HFpEF) affects more than 50% of HF patients worldwide, and more than 70% of HF patients aged over 65. This is a complex syndrome with a clinically heterogeneous presentation and a multifactorial pathophysiology, both of which make its diagnosis and treatment challenging. A Portuguese HF expert panel convened to address HFpEF pathophysiology and therapy, as we...


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