21 documents found, page 1 of 3
Validation of the Adult Asthma Epidemiological Score: a secondary analysis of E...
Laranjeira, Catarina; Jácome, Cristina; Amaral, Rita; Bernardo, Filipa; Correia-deSousa, Jaime; Fonseca, João A.; Amaral, RitaThe A2 score is an 8-question patient-reported outcome measure that has been validated for ruling in (score ≥4) and ruling out (score 0-1) asthma. However, this screening tool has been validated in a cohort similar to the derivation cohort used. This study aims to validate the predictive accuracy of the A2 score in a primary care population against general practitioner (GP) clinical assessment and to determine ...
Development and validation of an electronic daily control score for asthma (e-D...
Sousa-Pinto, Bernardo; Jácome, Cristina; Pereira, Ana Margarida; Regateiro, Frederico S.; Almeida, Rute; Czarlewski, Wienczyslawa; Kulus, MarekBackground Validated questionnaires are used to assess asthma control over the past 1–4 weeks from reporting. However, they do not adequately capture asthma control in patients with fluctuating symptoms. Using the Mobile Airways Sentinel Network for airway diseases (MASK-air) app, we developed and validated an electronic daily asthma control score (e-DASTHMA). Methods We used MASK-air data (freely available to ...
Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Contro...
Sousa-Pinto, Bernardo; Louis, Gilles; Rodrigues, Jorge; Giuliano, Antonio Francesco Maria; Baiardini, Ilaria; Braido, Fulvio; Czarlewski, WienczyslawaEQ-5D-5L (EuroQOL, 5 Domains, 5 Levels) is a widely used health-related quality-of-life instrument, comprising 5 domains. However, it is not known how each domain is impacted by rhinitis or asthma control.; This study was partly funded by a grant from the University of Liège, Belgium. MASK-air has been supported by EU grants (POLLAR, EIT Health; Structural and Development Funds, Région Languedoc Roussillon and ...
Comparative effectiveness of anti-IL5 and anti-IgE biologic classes in patients...
Pfeffer, Paul E.; Ali, Nasloon; Murray, Ruth; Ulrik, Charlotte; Tran, Trung N.; Maspero, Jorge; Peters, Matthew; Christoff, George C.Background: Patients with severe asthma may present with characteristics representing overlapping phenotypes, making them eligible for more than one class of biologic. Our aim was to describe the profile of adult patients with severe asthma eligible for both anti-IgE and anti-IL5/ 5R and to compare the effectiveness of both classes of treatment in real life. Methods: This was a prospective cohort study that inc...
Multidisciplinary development and initial validation of a clinical knowledge ba...
Pereira, Ana Margarida; Jácome, Cristina; Jacinto, Tiago; Amaral, Rita; Pereira, Mariana; Sá-Sousa, Ana; Couto, Mariana; Vieira-Marques, PedroMost mobile health (mHealth) decision support systems currently available for chronic obstructive respiratory diseases (CORDs) are not supported by clinical evidence or lack clinical validation. The development of the knowledge base that will feed the clinical decision support system is a crucial step that involves the collection and systematization of clinical knowledge from relevant scientific sources and its...
Profiling Persistent Asthma Phenotypes in Adolescents: A Longitudinal Diagnosti...
Amaral, Rita; Jácome, Cristina; Almeida, Rute; Pereira, Ana Margarida; Alves-Correia, Magna; Mendes, Sandra; Rodrigues, José Carlos CidraisWe aimed to identify persistent asthma phenotypes among adolescents and to evaluate longitudinally asthma-related outcomes across phenotypes. Adolescents (13-17 years) from the prospective, observational, and multicenter INSPIRERS studies, conducted in Portugal and Spain, were included (n = 162). Latent class analysis was applied to demographic, environmental, and clinical variables, collected at a baseline med...
Profiling Persistent Asthma Phenotypes in Adolescents: A Longitudinal Diagnosti...
Amaral, Rita; Jácome, Cristina; Almeida, Rute; Pereira, Ana Margarida; Alves-Correia, Magna; Mendes, Sandra; Rodrigues, José Carlos CidraisWe aimed to identify persistent asthma phenotypes among adolescents and to evaluate longitudinally asthma-related outcomes across phenotypes. Adolescents (13-17 years) from the prospective, observational, and multicenter INSPIRERS studies, conducted in Portugal and Spain, were included (n = 162). Latent class analysis was applied to demographic, environmental, and clinical variables, collected at a baseline med...
Profiling persistent asthma phenotypes in adolescents: A longitudinal diagnosti...
Amaral, Rita; Jácome, Cristina; Almeida, Rute; Pereira, Ana M.; Alves-Correia, Magna; Mendes, Sandra; Rodrigues, José C.; Carvalho, Joana; Araújo, LuísWe aimed to identify persistent asthma phenotypes among adolescents and to evaluate longitudinally asthma-related outcomes across phenotypes. Adolescents (13–17 years) from the prospective, observational, and multicenter INSPIRERS studies, conducted in Portugal and Spain, were included (n = 162). Latent class analysis was applied to demographic, environmental, and clinical variables, collected at a baseline med...
InspirerMundi—remote monitoring of inhaled medication adherence through objecti...
Pedro, Vieira-Marques; Rute, Almeida; Teixeira, João F.; Valente, José; Jácome, Cristina; Cachim, Afonso; Guedes, Rui; Pereira, Ana; Jacinto, TiagoThe adherence to inhaled controller medications is of critical importance for achieving good clinical results in patients with chronic respiratory diseases. Self-management strategies can result in improved health outcomes and reduce unscheduled care and improve disease control. However, adherence assessment suffers from difficulties on attaining a high grade of trustworthiness given that patient self-reports o...
A systematic review of asthma phenotypes derived by data-driven methods
Cunha, Francisco; Amaral, Rita; Jacinto, Tiago; Sousa-Pinto, Bernardo; Fonseca, João A.Classification of asthma phenotypes has a potentially relevant impact on the clinical management of the disease. Methods for statistical classification without a priori assumptions (data-driven approaches) may contribute to developing a better comprehension of trait heterogeneity in disease phenotyping. This study aimed to summarize and characterize asthma phenotypes derived by data-driven methods. We performed...