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Bowman-Birk protease inhibitor from Vigna unguiculata seeds enhances the action...
Álvares, Alice da Cunha Morales; Schwartz, Elisabeth Nogueira Ferroni; Amaral, Nathalia Oda; Trindade, Neidiane Rosa; Pedrino, Gustavo RodriguesThe hydrolysis of bradykinin (Bk) by different classes of proteases in plasma and tissues leads to a decrease in its half-life. Here, Bk actions on smooth muscle and in vivo cardiovascular assays in association with a protease inhibitor, Black eyed-pea trypsin and chymotrypsin inhibitor (BTCI) and also under the effect of trypsin and chymotrypsin were evaluated. Two synthetic Bk-related peptides, Bk1 and Bk2, w...
Date: 2017
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Origin: Oasisbr