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Identification and determination of the inulin content in the roots of the Nort...

Pontes, Ana Georgina Oliveira; Silva, Karine Lima; Fonseca, Said Gonçalvez da Cruz; Soares, Arlete Aparecida; Feitosa, Judith Pessoa de Andrade

A polysaccharide was extracted from the roots of Pombalia calceolaria, a plant used in folk medicine in Northeastern Brazil, by decoction followed by precipitation with methanol, yielding a concentration of 13.0% w/w, and purification with acetone. The molar mass peak was estimated to be 4.0 × 103 Da using gel permeation chromatography (GPC). Polarized light photomicrography of histological sections revealed th...

Date: 2021   |   Origin: Oasisbr

α-Lipoic acid as adjunctive treatment for schizophrenia : an open-label trial

Sanders, Lia Lira Olivier; Menezes, Carlos Eduardo de Souza; Chaves Filho, Adriano José Maia; Viana, Glautemberg de Almeida; Fechine, Francisco Vagnaldo

Purpose/Background: Accumulating evidence suggests an involvement of oxidative stress in the pathophysiology of schizophrenia. This offers a hypothesis-derived therapeutic approach to hinder oxidative damage and its clinical sequelae. α-Lipoic acid (ALA) is a powerful natural antioxidant indicated to treat diabetic neuropathy. Methods/Procedures: In this pilot investigation, we administered ALA (100 mg/d) for 4...

Date: 2018   |   Origin: Oasisbr

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