4 documents found, page 1 of 1
Cryoglobulinemic Vasculitis Stemming from Delayed Recognition of Rheumatoid Art...
Monteiro, Ana Carolina; Valadão , Ivone; França de Santana, Tomás; Fonseca, TomásA vasculite crioglobulinémica (VC) é uma doença mediada por imunocomplexos com envolvimento multiorgânico e uma apresentação clínica heterogénea. A VC tem sido documentada em doentes com artrite reumatoide (AR), mas a sua incidência é atualmente rara devido ao diagnóstico precoce e à instituição de terapêutica adequada para a AR, incluindo fármacos biológicos modificadores da doença. Reportamos o caso de uma do...
Fatal Case of Immune-Related Myocarditis and Myositis Due to Treatment with Imm...
Queirós Coelho, João; Simões, Joana; Fonseca, Tomás; Xavier Azevedo, Sérgio; Araújo, AntónioImmune checkpoint inhibitor and tyrosine kinase inhibitor combinations have become the new standard of care in the first-line treatment of metastatic clear cell renal cell carcinoma. However, there is a growing concern regarding severe immune-related adverse events. A 78-year-old man with metastatic clear cell renal cell carcinoma, treated with pembrolizumab and axitinib, was admitted to the emergency departmen...
Uncommon Debut: Orbital Pseudotumor as the Initial Presentation of IgG4-Related...
Monteiro, Ana Carolina; Rubim Correia , Ana; Fonseca, Tomás
Intrahospital Protocol for the Management of COVID-19 Disease in Adults
Barreiro, Ivo; Matos, Marta; de Oliveira, Miguel; Guerra, Diogo; Fonseca, Tomás; Abreu, Miguel; Morais, Sara; Barbosa, GustavoThe COVID-19 pandemic is currently responsible for over 526 million infections and over 6.3 million deaths. As a new disease, the number of papers on the subject is extensive, motivating considerable heterogeneity in its approach. Despite some medicines having sound evidence of benefit, new interventions and strategies continue to be proposed, and some still lack scientific evidence, which hinders a uniform and...