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Sensitivity and detection of chikungunya viral genetic material using several P...

Esposito,Danillo Lucas Alves; Fonseca,Benedito Antonio Lopes da

Abstract INTRODUCTION: Chikungunya fever is a condition resulting from infection by chikungunya virus (CHIKV), an Aedes sp.-transmitted virus. This disease has been diagnosed in thousands of cases in the Americas, particularly in Brazil, in recent years, and there is an ongoing epidemic of chikungunya fever in Brazil that began in 2014. Clinical diagnosis is difficult; only a few cases have been confirmed by la...

Date: 2017   |   Origin: Oasisbr

Will Mayaro virus be responsible for the next outbreak of an arthropod-borne vi...

Esposito,Danillo Lucas Alves; Fonseca,Benedito Antonio Lopes da

Abstract Mayaro virus is an alphavirus from the Togaviridae family and is transmitted mainly by Hemagogus mosquitoes. This virus circulates in high-density tropical forests or rural areas of Central and South America causing a disease characterized by high-grade fever, maculopapular skin rash and marked arthralgia that, in some patients, can persist for long periods after infection and may be misinterpreted as ...

Date: 2017   |   Origin: Oasisbr

Dengue vaccines: what we know, what has been done, but what does the future hold?

Abrão,Emiliana Pereira; Espósito,Danillo Lucas Alves; Lauretti,Flávio; Fonseca,Benedito Antonio Lopes da

Dengue, a disease caused by any of the four serotypes of dengue viruses, is the most important arthropod-borne viral disease in the world in terms of both morbidity and mortality. The infection by these viruses induces a plethora of clinical manifestations ranging from asymptomatic infections to severe diseases with involvement of several organs. Severe forms of the disease are more frequent in secondary infect...

Date: 2015   |   Origin: Oasisbr

Efeito das drogas anti-retrovirais sobre as taxas de fertilidade de ratas Wistar

Figueiró Filho,Ernesto Antonio; Duarte,Geraldo; Silva,Alzira Amélia Martins Rosa e; Fonseca,Benedito Antonio Lopes da; Mussi-Pinhata,Marisa Márcia

OBJETIVO: avaliar os efeitos de drogas anti-retrovirais isoladas e em associação sobre as taxas de fertilidade em ratas prenhes expostas a estes fármacos, bem como o efeito perinatal nas crias. MÉTODOS: foram utilizadas ratas fêmeas prenhes adultas da raça Wistar, pesando inicialmente entre 200 e 230 g. Foram testadas a azidotimidina (AZT), lamivudina (3TC) e nelfinavir (NFV), cujas dosagens foram padronizadas ...

Date: 2002   |   Origin: Oasisbr

Epidemiologia da infecção pela dengue em Ribeirão Preto, SP, Brasil

Rodrigues,Eugênia Maria Silveira; Dal-Fabbro,Amaury Lélis; Salomão,Rogério; Ferreira,Ivani Bisordi; Rocco,Iray Maria; Fonseca,Benedito Antonio Lopes da

OBJETIVO: Avaliar a transmissão de dengue em uma instituição correcional de adolescentes localizada em Ribeirão Preto, SP, Brasil. MÉTODOS: Foi realizado um inquérito sorológico e virológico da população de internos e funcionários de uma instituição correcional de adolescentes infratores localizada em Ribeirão Preto, SP, Brasil. A população de estudo consistiu em 105 menores e 91 funcionários que representavam ...

Date: 2002   |   Origin: Oasisbr

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