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Padronização de método de concentração e extração de ácidos nucleicos em amostr...

Cabral,Aline Diniz; Claro,Ieda Carolina Mantovani; Augusto,Matheus Ribeiro; Friolani,Veronica Nikoluk; Bezerra,Cintia de Espindola

RESUMO A vigilância da qualidade dos esgotos sanitários pode representar uma ferramenta complementar para monitoramento de doenças infecciosas e prevenção de surtos epidêmicos, especialmente quando a capacidade para testes clínicos é limitada. Dessa maneira, o presente estudo descreve o detalhamento técnico de um método de baixo custo para a concentração e extração de ácidos nucleicos de amostras de esgoto sani...

Date: 2021   |   Origin: Oasisbr

Effects of Physical Training on the Myocardium of Oxariectomized LDLr Knockout ...

Brianezi,Ledimar; Ornelas,Elisabete; Gehrke,Flávia de Sousa; Fonseca,Fernando Luiz Affonso; Alves,Beatriz da Costa Aguiar

Abstract Background: The emergence of coronary heart disease is increased with menopause, physical inactivity and with dyslipidemia. Physical training is known to promote the improvement of cardiovascular functions. Objective: To investigate the effects of aerobic physical training on the left ventricle in ovariectomized LDL knockout mice. Methods: Thirty animals were divided into 6 groups (n = 5): Sedentary no...

Date: 2020   |   Origin: Oasisbr

Dosages of androgenic hormones in adolescent patients with severe acne

Cunha,Marisa Gonzaga da; Moraes,Caio; Cebrian,Giovana; Silva,Rafaela Ferreira da; Reple,Sônia Isabel Friedlaender; Machado Filho,Carlos D’Apparecida

SUMMARY OBJECTIVE Acne vulgaris in female adolescents, when severe or accompanied by other signs of androgenization, may represent a sign of hyperandrogenemia often underdiagnosed, which will have harmful consequences for adult life. The objective of this cross-sectional and retrospective study was to demonstrate the incidence of hormonal changes in the cases of female adolescents with severe or extensive acne,...

Date: 2020   |   Origin: Oasisbr

Association between changes in body fat distribution, biochemical profile, time...

Soares,Lismeia Raimundo; Menezes,Gabriella Coelho; Barreto,Ana Paula Menna; Sant’Anna,Mônica de Souza Lima; Cardoso,Nadir Machado Alves

SUMMARY OBJECTIVES Individuals living with HIV seem to be more prone to changes in the redistribution of body fat, characterized as lipodystrophy, which may occur in conjunction with metabolic diseases. In the present study, such impacts were assessed in adults with and without HIV and associated with the time of virus diagnosis and treatment with antiretroviral. METHODS A cross-sectional study with 123 adults,...

Date: 2020   |   Origin: Oasisbr

Effects of nasal aspiration by the Proetz® method in pediatric patients with si...

Filgueira,Yaskara Amorim; Holanda,Vanderlan Nogueira; Fonseca,Fernando Luiz Affonso; Feder,David

SUMMARY OBJECTIVE: To characterize the effects of nasal aspiration with Proetz® in peak nasal inspiratory flow (PNIF) in pediatric sinusitis (PS) patients with nasal obstruction. METHODS: This is a non-randomized descriptive-analytical clinical trial with a quantitative approach. The sample comprised 30 children. Initially, the PNIF was measured and the Visual Analogical Scale (VAS) was used for nasal obstructi...

Date: 2020   |   Origin: Oasisbr

Irisin and troponin I expression in dialysis patients submitted to remote ische...

Gehrke,Flávia de Sousa; Gouveia,Mariana Carvalho; Barbosa,Carla Gabriela Marques; Murad,Neif; Reis,Beatriz da Costa Aguiar Alves

ABSTRACT Background: Renal replacement therapy continues to be related to high hospitalization rates and poor quality of life. All-cause morbidity and mortality in renal replacement therapy in greater than 20% per year, being 44 times greater when diabetes is present, and over 10 times that of the general population. Regardless of treatment, the 5-year survival is 40%, surpassing many types of cancers. Irisin i...

Date: 2020   |   Origin: Oasisbr

Evaluation of Collagen Fibers, MMP2, MMP9, 8-OHdG and Apoptosis in the Aorta of...

Maifrino,Laura Beatriz M.; Lima,Nathalia E. A. de; Marques,Mara R.; Cardoso,Clever G.; Souza,Lidiane B. de; Tomé,Tabata de Carvalho

Abstract Background: In menopause, there is greater cellular exposure to oxidative stress, related to the decreased antioxidative effects of estrogen. These metabolic changes favor the progression of cardiovascular diseases, such as atherosclerosis. Abnormal function of the aorta - the most important artery - is associated with many cardiovascular diseases. Collagen, especially types I and III, is one of the mo...

Date: 2019   |   Origin: Oasisbr

The sensitivity, specificity, and agreement of a point of care method: an asses...

Maciel,Erika da Silva; Quaresma,Fernando Rodrigues Peixoto; Figueiredo,Francisco Winter dos Santos; Sarraf,Jonathan Souza; Luis,Taynah Putty

Abstract The use of new technologies can improve screening in communities with difficult access to health. This article aims to evaluate the sensitivity, specificity, and agreement of a point of care test in comparison to laboratory methods for the determination of glucose (GLI), triglyceride (TG), and total cholesterol (TC) concentrations. This prospective study used data from the remaining adult population of...

Date: 2019   |   Origin: Oasisbr

Metabolic and volume status evaluation of hemodialysis patients with and withou...

Almeida,Lenina Ludimila Sampaio de; Sette,Luís Henrique Bezerra Cavalanti; Fonseca,Fernando Luiz Affonso; Bezerra,Leila Silveira Vieira da Silva

Abstract Introduction: It is unclear whether residual renal function (RRF) in dialysis patients can attenuate the metabolic impact of the long 68-hour interdialytic interval, in which water, acid, and electrolyte accumulation occurs. Objective: to evaluate serum electrolyte levels, water balance, and acid-base status in dialytic patients with and without RRF over the long interdialytic interval (LII). Methodolo...

Date: 2019   |   Origin: Oasisbr

The role of Survivin as a biomarker and potential prognostic factor for breast ...

Veiga,Glaucia Luciano da; Silva,Raissa Daniel Machado da; Pereira,Edimar Cristiano; Azzalis,Ligia Ajaime; Alves,Beatriz da Costa Aguiar

SUMMARY Breast cancer (BC) is one of the primary health problems worldwide. As the most common cancer in women in the world and in Brasil, behind only non-melanoma skin cancer, this neoplasm corresponds to approximately 28% of new cases per year in the country. BC also affects men, although the incidence corresponds to only 1% of total cases. Currently, most of the chemotherapeutic agents used in BC treatment a...

Date: 2019   |   Origin: Oasisbr

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