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Hemoglobin A2 values in sickle cell disease patients quantified by high perform...
Fonseca,Silvana Fahel da; Amorim,Tatiana; Purificação,Antônio; Gonçalves,Marilda; Boa-Sorte,NeyBACKGROUND: In sickle cell disease, the quantification of Hb A2 is important for the differential diagnosis between sickle cell anemia (Hb SS) and Hb S/ß0-thalassemia.OBJECTIVE: To determine Hb A2 levels as quantified by high performance liquid chromatography in patients with sickle cell anemia (Hb SS) and with the SC hemoglobinopathy, with or without concomitant alpha thalassemia.METHODS: This is a retrospecti...
Breastfeeding and the anthropometric profile of children with sickle cell anemi...
Nogueira,Zeni Drubi; Boa-Sorte,Ney; Leite,Maria Efigênia de Queiroz; Kiya,Márcia Miyuki; Amorim,Tatiana; Fonseca,Silvana Fahel daOBJECTIVE: To study the breastfeeding history (BF) and the anthropometric status of children with Sickle Cell Disease (SCD). METHODS: A cross-sectional study of 357 children with SCD aged between 2 and 6 years, regularly followed at a Newborn Screening Reference Service (NSRS) between November 2007 and January 2009. The outcome was anthropometric status and the exposures were: BF pattern, type of hemoglobinopat...
National neonatal screening program for hemoglobinopathies: how far have we adv...
Fonseca,Silvana Fahel da
Spinal cord compression in b-thalassemia: follow-up after radiotherapy
Fonseca,Silvana Fahel da; Figueiredo,Maria Stella; Cançado,Rodolfo Delfini; Nakandakare,Fernando; Segreto,Roberto; Kerbauy,JoséCONTEXT: Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including <FONT FACE="Symbol">b</font>-thalassemia. CASE REPORT: We report the case of a patient with intermediate <FONT FACE="Symbol">b</font>-thalassemia and crural paraparesis due to spinal cord compression by a paravertebral extramedullary mass. Sh...