Objectives: To analyze the clinical and laboratory characteristics of patients with sporadic and familial central precocious puberty (CPP) followed at a reference service in northeastern Brazil. Methodology: Descriptive study, with retrospective analysis of medical records, and cross-sectional study, with analysis of a questionnaire on consanguinity and family history of precocious puberty. Results: Sixty-two g...
Objective: To propose a waist-to-height ratio (WtHR) cutoff point for metabolic risk in Brazilian Turner syndrome (TS) patients. Methods: Retrospective study of anthropometric, clinical and biochemical data related to the metabolic syndrome (MS) of 45 TS patients at a specialized center. The accuracy and area under the receiver operating characteristic (ROC) curve of body mass index (BMI), waist circumference (...
Objective: Although hypothyroidism has been linked to oxidative stress, data regarding the relationship between thyroid hormone levels and oxidative stress is still inconsistent. This study was designed to evaluate the effect of levothyroxine replacement on oxidative stress in women with primary hypothyroidism. Design: A total of 25 female patients with primary hypothyroidism were included. Oxidative stress mar...
Hyperglycemia is a frequent complication and its prevalence occurs in up to 38% of hospitalized patients. Such condition may be due to previously known diabetes, stress responsive to associated diseases or treatments or it may due to diabetes only diagnosed during hospitalization. The presence of nosocomial hyperglycemia is associated with prolonged hospitalization time, increased demand for human resources and...
Objectives: Turner syndrome affects approximately one in 2500 live-born females and results from the complete or partial absence of the second sex chromosome. Although hypogonadism and infertility are the most frequent features, 2-5% may present spontaneous pregnancy. The purpose of this paper is to report the outcome of a spontaneous pregnancy in a patient with Turner syndrome and to review management of this ...
Introdução: a conversão de testosterona em estradiol ocorre pela ação da enzima aromatase. Inibidores da aromatase retardam o fechamento das epífises e prolongam o tempo de crescimento linear. Objetivo: relatar a evolução do tratamento com o inibidor da aromatase, anastrozol, em um paciente com baixa estatura idiopática e apresentar uma breve revisão sobre o uso desta classe terapêutica nesse contexto clínico. ...