7 documents found, page 1 of 1
Five-Year Outcome in Stroke Patients Submitted to Thrombolysis
Machado, C; Pinho, J; Alves, JN; Santos, AF; Ferreira, MC; Abreu, MJ; Oliveira, L; Mota, J; Fontes, JR; Ferreira, CBACKGROUND AND PURPOSE: Little is known on long-term follow-up after thrombolysis in ischemic stroke patients because the majority of studies evaluated outcome at 3 to 12 months. We aimed to assess 5-year outcome after intravenous thrombolysis (IVT). METHODS: Cohort study based on the prospective registry of all consecutive ischemic stroke patients submitted to IVT in our Stroke Unit. Five-year outcome, includi...
Intravenous thrombolysis is more effective in ischemic cardioembolic strokes th...
Rocha, S; Pires, A; Gomes, J; Sousa, F; Pinho, J; Rodrigues, M; Ferreira, C; Machado, A; Maré, R; Fontes, JRIt was suggested that intravenous thrombolysis (IT) leads to larger extent recanalization in cardioembolic stroke. In this work we assess if this has beneficial clinical traduction. METHOD: We evaluated 177 patients undergoing IT, which were categorized into cardioembolic (CE) and non-cardioembolic (NCE). National Institutes of Health Stroke Scale (NIHSS) and modified Rankin scale were compared. RESULTS: The me...
Trombose Venosa Cerebral com Hipertensão Intracraniana: quando a terapêutica mé...
Rocha, S; Rodrigues, M; Maré, R; Ferreira, C; Fontes, JR
A trombólise endovenosa é mais eficaz nos acidentes vasculares cerebrais isquêm...
Rocha, S; Rocha, J; Sousa, F; Pinho, J; Rodrigues, M; Ferreira, C; Machado, A; Mare, R; Fontes, JRIt was suggested that intravenous thrombolysis (IT) leads to larger extent recanalization in cardioembolic stroke. In this work we assess if this has beneficial clinical traduction. METHOD: We evaluated 177 patients undergoing IT, which were categorized into cardioembolic (CE) and non-cardioembolic (NCE). National Institutes of Health Stroke Scale (NIHSS) and modified Rankin scale were compared. RESULTS: The me...
Cerebral venous thrombosis in a patient with localised scleroderma
Rocha, J; Pinho, J; Fernandes, J; Ferreira, C; Macedo, C; Fontes, JR; Perdigão, S
Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese pat...
Rosa, A; Fonseca, BV; Krug, T; Manso, H; Gouveia, L; Albergaria, I; Gaspar, G; Correia, M; Viana-Baptista, M; Simões, RM; Pinto, AN; Taipa, RBACKGROUND: The genetic contribution to stroke is well established but it has proven difficult to identify the genes and the disease-associated alleles mediating this effect, possibly because only nuclear genes have been intensely investigated so far. Mitochondrial DNA (mtDNA) has been implicated in several disorders having stroke as one of its clinical manifestations. The aim of this case-control study was to ...
Kalirin: a novel genetic risk factor for ischemic stroke
Krug, T; Manso, H; Gouveia, L; Sobral, J; Xavier, JM; Albergaria, I; Gaspar, G; Correia, M; Viana-Baptista, M; Simões, RN; Pinto, AN; Taipa, RCerebrovascular and cardiovascular diseases are the leading causes of death and disability worldwide. They are complex disorders resulting from the interplay of genetic and environmental factors, and may share several susceptibility genes. Several recent studies have implicated variants of the Kalirin (KALRN) gene with susceptibility to cardiovascular and metabolic phenotypes, but no studies have yet been perfo...