4 documents found, page 1 of 1
Cognitive impairment in prostate cancer patients receiving androgen deprivation...
Barreira, João Vasco; Barreira, Pedro; Falcão, Gil; Garcez, Daniela; Silva, Pedro; Santos, Gustavo; Fontes-Sousa, Mário; Mendes, José Leão; Reis, FilipaBackground: Androgen deprivation therapy (ADT) is a primary treatment for prostate cancer (PCa) that effectively reduces androgen levels to suppress tumor progression. However, growing evidence suggests potential cognitive side effects, raising concerns about the long-term neurological consequences of this treatment. Objective: This scoping review aims to synthesize the existing evidence linking ADT to cognitiv...
Case report: Primary CDK4/6 inhibitor and endocrine therapy in locally advanced...
Vilhais, Guilherme; Alpuim Costa, Diogo; Fontes-Sousa, Mário; Ribeiro, Pedro Casal; Martinho, Filipa; Botelho de Sousa, CarolinaLocally advanced breast cancer poses significant challenges to the multidisciplinary team, in particular with hormone receptor (HR) positive, HER2-negative tumors that classically yield lower pathological complete responses with chemotherapy. The increasingly significant use of CDK 4/6 inhibitors (CDK4/6i) plus endocrine therapy (ET) in different breast cancer settings has led to clinical trials focusing on thi...
Impact of the COVID-19 pandemic on breast cancer management in Portugal: a cros...
Alpuim Costa, Diogo; Gonçalves Nobre, José Guilherme; Fernandes, João Paulo; Batista, Marta Vaz; Simas, Ana; Sales, Carolina; Gouveia, HelenaIntroduction: Cancer care providers have faced many challenges in delivering safe care for patients during the COVID-19 pandemic. This cross-sectional survey-based study investigated the impact of the pandemic on clinical practices of Portuguese medical oncologists caring for patients with breast cancer. Methods: An anonymous online survey comprising 42 questions gathered information regarding COVID-19 testing,...
PROGNOSTIC IMPACT OF WEIGHT LOSS, INFLAMMATION BIOMARKERS AND INFLUENCE OF THE ...
Vasconcelos de Matos, Leonor; Coelho, Andreia; Neves, Maria Teresa; Fernandes, Leonor; Cunha, Renato; Fontes-Sousa, Mário; Malheiro, MarianaINTRODUÇÃO: O adenocarcinoma do pâncreas (AP) constitui uma das mais mortais neoplasias malignas, com < 10% dos doentes vivos ao fim de um ano. M ais de 80% dos doentes com AP desenvolvem caquexia, a co-morbilidade mais marcante deste cancro. O síndrome caquexia-anorexia representa uma entidade sistémica de perda de peso (PP) intencional, não completamente reversível por adequado suporte nutricional. A infla...