The goal of this work was to examine whether elevated iodine intake was associated with adverse effects on IQ among school-age children in Portugal. In a representative sample of children from the north of the country, IQ percentiles by age (assessed with Raven’s Colored Progressive Matrices) were dichotomized to <50 (“below-average” IQs) and ≥50. Morning urine iodine concentrations, corrected for creatinine, w...
The goal of this work was to examine whether elevated iodine intake was associated with adverse effects on IQ among school-age children in Portugal. In a representative sample of children from the north of the country, IQ percentiles by age (assessed with Raven’s Colored Progressive Matrices) were dichotomized to <50 (“below-average” IQs) and ≥50. Morning urine iodine concentrations, corrected for creatinine, w...
Key Points: - Blood ammonia levels should be measured in every encephalopathy of unknown origin, especially when an intoxication cause is thought; - Late-onset inherited metabolic disorders may only manifest in the presence of triggering environmental factors such as some drugs (e.g. anti-epileptics); an undiagnosed metabolic disorder should be considered in such cases.
Phthalates are a group of chemical compounds used as plasticizers in the manufacture of plastic materials. They can be present in many commonly used products. There seems to be a relationship between exposure to phthalates and the occurrence of metabolic dysfunctions, such as a decrease in glucose tolerance, oxidative stress, loss of beta cells, and a decrease in insulin synthesis. As beta cells play a key role...
Introdução: Há evidência que adolescentes com a mesma idade cronológica mas com estádios pubertários distintos têm comportamentos psicossociais diferentes. Desconhece-se, no entanto, se existe alguma relação entre o ritmo de maturação pubertária e o desenvolvimento do córtex pré-frontal e sistema límbico. Objetivo: Pretendeu-se com este trabalho avaliar através de ressonância magnética, o desenvolvimento cerebr...
The World Health Organization promotes salt iodisation to control iodine deficiency. In Portugal, the use of iodised salt in school canteens has been mandatory since 2013. The present study aimed to evaluate iodine status in school-aged children (6-12 years) and to monitor the use of iodised salt in school canteens. A total of 2018 participants were randomly selected to participate in a cross-sectional survey i...
A baixa estatura é uma das causas mais frequentes de consulta de Pediatria e de Endocrinologia Pediátrica. São variadas as causas que podem diminuir a velocidade de crescimento e originar uma baixa estatura. Por vezes não é possível encontrar anomalias e nestas condições coloca-se o diagnóstico de exclusão de baixa estatura idiopática. Este grupo nosológico engloba uma variedade de situações, nele se incluindo ...
Resumo: A insuficiência suprarrenal é rara na idade pediátrica. Uma das suas causas é a doença de Addison cuja incidência é muito inferior à verificada no adulto. Apresenta-se o caso de uma criança do sexo feminino, com seis anos, internada por vómitos incoercíveis e desidratação hiponatrémica moderada associada a hipercaliémia. Como antecedentes apresentava má evolução estaturoponderal desde os três anos. No ...