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Matrix metalloproteinases in focus: an exploratory epidemiological study in a N...

Foresti, Manon; Garcia, Catarina; Gonçalves, Maria; Relvas, Marta; Viana da Costa, Alexandra

Background: Matrix metalloproteinases (MMPs) are zinc-dependent enzymes that regulate extracellular matrix degradation and remodelling. Among them, MMP-8 and MMP-9 are key mediators of inflammation, tissue remodelling, and wound healing. They have been implicated in both type 1 diabetes mellitus (T1DM) and periodontal disease (PD) [1]. The literature indicates a bidirectional association between T1DM and PD: ch...

Date: 2025   |   Origin: Scientific Letters
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