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Proteomics characterization of human uterine samples during reproductive ageing

Dias, Bruna; Formoso, Inês; Guedes-Martins, Luís; Almeida, Henrique; Silva, Elisabete; Silva, André M.N.; Matos, Liliana

Nowadays, postponing motherhood has become more common in modern societies. Such decision rises major social and health concerns, as advanced maternal age associates with low fertility, pregnancy complications and a greater need for assisted reproductive techniques. Female reproductive ageing is associated with alterations that are particularly evident in the ovaries. Yet, given the pivotal contribution of the ...


Unveiling uterine senescence and its potential role in age-related female ferti...

Formoso, Inês; Guedes-Martins, Luís; Almeida, Henrique; Silva, Elisabete; Matos, Liliana

Nowadays, infertility is a major topic present in public health discussions due to its increased prevalence worldwide. With time, female infertility rates have increased, mainly, because women are delaying childbearing to their late 30s/early 40s, leading to fertility decline, complications during gestation, and a higher demand for assisted reproductive techniques. Uterine alterations have been pointed out as a...


Proteomics Characterization of Human Uterine Samples During Reproductive Ageing

Dias, Bruna; Formoso, Inês; Martins, Luís Guedes; Almeida, Henrique; Silva, Elisabete; Silva, André M.N.; Matos, Liliana


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