19 documents found, page 1 of 2

From resistance to sensitivity in non-small cell lung cancer: newly established...

Background: Non-small cell lung cancer (NSCLC) is the most common form of lung cancer and presents a low 5-year survival rate [1]. Standard treatment of NSCLC includes chemotherapeutic drugs, such as taxanes and platinum-based agents. However, cancer cells may acquire resistance to multiple unrelated chemotherapeutic agents, known as multidrug resistance (MDR), which significantly limits treatment options [2]. ...

Identification and Characterization of Myeloid-Derived Suppressor Cells (MDSC) ...

Introduction: Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that accumulate under pathological conditions, such as cancer, and suppress immune responses through various mechanisms. Distinguishing MDSC populations remains challenging due to their shared surface markers with neutrophils and monocytes, complicating accurate identification and quantification. This...

Oncology Education in PALOP: Challenges and Opportunities for Strengthening Hea...

This article analyzes the current landscape of Oncology education in Portuguese-speaking African countries (PALOP), identifying challenges and proposing strategies to strengthen oncology training. The rising incidence of oncological diseases in these countries, combined with the shortage of specialised professionals, highlights the urgent need for investment in oncology education. The article discusses approach...

Robotic Distal Pancreatectomy for Intraductal Oncocytic Papillary Neoplasm

Robotic distal pancreatectomy has become an established approach for the management of pancreatic body and tail lesions, offering enhanced dexterity, improved visualization, and refined dissection around critical vascular structures. A 55-year-old man with hypertension, a history of smoking, and chronic alcohol abuse presented with progressive upper abdominal pain and postprandial bloating. MRI and CT identifie...

Indocyanine Green–Guided Robotic Low Anterior Resection for Rectal Cancer: A St...

The treatment of locally advanced rectal adenocarcinoma is based on a multimodal approach, including total mesorectal excision1. Robotic surgery provides a three-dimensional visualization, a stable image, and greater precision in pelvic dissection, allowing better control over critical structures2. The use of indocyanine green fluorescence enables real-time assessment of anastomotic perfusion, enhancing anastom...

IMPLEMENTING TEXTBOOK ONCOLOGIC OUTCOME IN THE DEPARTMENT OF SURGICAL ONCOLOGY ...

Background: Textbook Oncologic Outcome (TOO) serves as a comprehensive quality metric, representing the optimal outcome for oncological patients undergoing therapeutic surgery and, consequently, indicating the quality of healthcare provided. Methods: The TOO variables were applied to the entire cohort of adult patients (≥18 years of age) diagnosed with esophagus, stomach, pancreas, colon, rectum, urinary bladde...

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PRE-SURGICAL NUTRITIONAL STATUS AND SURGICAL COMPLICATIONS IN PATIENTS WITH DIG...

Introduction: Malnutrition is present in 40-50% of surgical patients upon hospital admission and is one of the most important factors influencing post-surgical morbidity and mortality. It is important to establish routines to identify and monitor patients at nutritional risk nutritional, to start early nutritional therapy, ideally in the pre-surgical phase. The aim of this study was to evaluate the association ...

SURGICAL RISK ASSESSMENT IS CRUCIAL TO MITIGATE POSTOPERATIVE COMPLICATIONS

Postoperative complications often determine the failure of a meticulous and adequate surgical intervention. The surgical risk assessment allows the identification of patients who can benefit from a program to optimize their general condition, reducing the risk of postoperative complications. The purpose of this article is to address the main factors associated with increased perioperative risk as well as the mo...