3 documents found, page 1 of 1
Anti-inflammatory and toxicity studies of atranorin extracted from Cladina kalb...
Melo, Marcelia Garcez Dória de; Araújo, Adriano Antunes de Souza; Serafini, Mairim Russo; Carvalho, Larissa Feitosa; Bezerra, Marília dos SantosAtranorin (ATR) is the main compound from the lichen Cladina kalbii Ahti, which grows in the arid regions of northeastern Brazil. This study was conducted to evaluate the anti-inflammatory and toxicological properties of ATR. To evaluate anti-inflammatory properties, paw edema was induced by injecting 0.1 mL of carrageenan into the subplantar region of the right hind paw of rats, and leukocyte migration was ind...
Pre-clinical toxicity of Morinda citrifolia Linn. leaf extract
Serafini, Mairim Russo; Santos, Rodrigo Correia; Dória, Grace Anne Azevedo; Jesus, Josepha Yohanna de; Melo, Marcelia Garcez Dória deThis investigation was carried out to evaluate the safety of an aqueous extract of Morinda citrifolia leaves (AEMC) by determining its potential toxicity after acute administration (5 g/kg) in rodents and cytotoxic studies. General behavior adverse effects and mortality were determined for up to 14 days. Biochemical and hematological parameters were determined after 14 days. Cytotoxic effects of the AEMC were d...
Anti-inflammatory and toxicity studies of atranorin extracted from Cladina kalb...
Melo, Marcelia Garcez Dória de; Araújo, Adriano Antunes de Souza; Serafini, Mairim Russo; Carvalho, Larissa Feitosa; Bezerra, Marília SantosAtranorin (ATR) is the main compound from the lichen Cladina kalbii Ahti, which grows in the arid regions of northeastern Brazil. This study was conducted to evaluate the anti-inflammatory and toxicological properties of ATR. To evaluate anti-inflammatory properties, paw edema was induced by injecting 0.1 mL of carrageenan into the subplantar region of the right hind paw of rats, and leukocyte migration was ind...