ABSTRACT Objective: The role of bone markers on insulin resistance (IR) remains controversial. The objective of this study is to evaluate the association between bone mineral density (BMD) and glucose metabolism and investigate if visceral hyperadiposity, evaluated by waist circumference (WC), is an effect modifier of this association. Subjects and methods: Cross-sectional analysis with 468 young adults from th...
INTRODUCTION AND OBJECTIVES: To investigate the effects of ethanol, diabetes mellitus and the combination of both on mouse fetuses. METHODS: We used 24 female Swiss mice, dividing them into four groups of 6 each: control (C), ethanol (E), diabetes (D) (blood glucose > 200 mg/dL) and diabetes + ethanol (DE). Diabetes was induced by alloxan (40 mg/kg) on day 7 of pregnancy. Groups E and DE received 4 g/kg of 25% ...
INTRODUÇÃO: Em populações não selecionadas, obstruções em vasos de fino calibre são mais susceptíveis à reestenose após intervenção coronária percutânea (ICP). Por isso, entre as características angiográficas preditoras do fenômeno, o diâmetro luminal de referência (D.L.R.) é particularmente relevante. Tais resultados são corroborados por ultra-sonografia intracoronária (USIC), evidenciando a influência das dim...
CONTEXT AND OBJECTIVE: Diabetes mellitus is a clinical syndrome that frequently leads to the development of chronic complications and high susceptibility to infections. It is probably due to defective immunological defense, which may be related to metabolic control of the disease. The aim of this study was to evaluate the effect of metabolic control on immune-cell behavior in type 1 and type 2 diabetic patients...
Enamel hypoplasia is an important clinical problem commonly seen in children born to diabetic women. We aimed to characterize the enamel hypoplasia in Wistar rats born to alloxan-induced diabetes mellitus rats. Groups consisted of pregnant rats supplemented (ISDR) or not (NISDR) with insulin and controls, in which sterile saline solution was administered instead of alloxan or insulin. The mandibular incisors of...
CONTEXT: Diabetes mellitus prevalence has been increasing worldwide due to factors like lifestyle changes and higher life expectancy. The Brazilian Multicenter Study performed between 1986 and 1988 evaluated the prevalence of diabetes and impaired glucose tolerance. OBJECTIVE: To assess the prevalence of diabetes and impaired glucose tolerance in the urban population aged 30-69 years of the city of Ribeirão Pre...
O estudo analisou fatores de risco para complicações em pés de pessoas com diabetes em Unidade Ambulatorial. Os dados foram obtidos por meio de entrevista semi-estruturada, avaliação de pés e exames laboratoriais. Os riscos tiveram a análise segundo Zavala e Braver e Sistema de Classificação do Consenso Internacional sobre Pé Diabético, mediante estatística descritiva. Nos resultados, a idade média foi 53,3±13 ...
CONTEXT: The association between psoriasis and hypoparathyroidism has been reported by several authors, and it has been suggested that abnormalities in calcium homeostasis may be involved in the development or exacerbation of psoriasis. However, so far there have only been two reports of pseudohypoparathyroidism associated with psoriasis. OBJECTIVE: To describe the familial occurrence of this association for th...
Objetivo: avaliar a relação entre o uso de sulfoniluréias (SF) por gestantes diabéticas seguidas na nossa clínica e as malformações (MF) fetais detectadas. Métodos: estudamos, retrospectivamente, 35 gestantes diabéticas tipo 2, seguidas no Ambulatório de Pré-Natal Patológico do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, USP, no período de 1993-1995, das quais 22 encontravam-se em uso inad...